Detaylı Arama
İptal
Bulunan: 28 Adet 0.001 sn
- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır.
- İptal tuşuna basarak normal aramaya dönebilirsiniz.
Filtreler
Filtreler
Bulunan: 28 Adet 0.001 sn
Yayın Türü : Konferans Bildirisi ✕Koleksiyon : Tıp Fakültesi ✕
Koleksiyon [2]
İlgili Araştırmacılar [19]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [1]
Yazar/lar [20]
Atıf Dizini [3]
Konu Başlıkları [20]
Yayıncı [20]
Dergi Adı [1]
Yayın Tarihi [6]
Dergi Sayısı [1]
Yayın Dili [3]
dc.description.provenance [20]
Erişime Açık

In vitro anti-candidal and anti-biofilm activity of new ethane sulfonyl hydrazone compound

ÖZTÜRK, Ali | AYDIN, Merve | ÖZDEMİR ÖZMEN, Ümmühan

Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. However, the emergence of resistance to the most common antifungal drugs, also due to biofilm formation, there is an increasing need to design new and more effective antifungals with less toxic. Sulfonyl hydrazones are well-known for their pharmacological effects, such as antifungal and antibacterial potential and can act as an antinociceptive, antidepressant, antineoplastic activity. The aim of this study was to investigate the anti-candidal and anti-biofilm activity o ...Daha fazlası

Konferans Bildirisi 2019 7 Görüntülenme
Erişime Açık

In vitro antifungal and antibiofilm activities of new butane sulfonyl hydrazone compound against medically important yeast

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan

The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası

Konferans Bildirisi 2019 11th Balkan Congress of Microbiology – Microbiologia Balkanica 2019, 6 Görüntülenme
Erişime Açık

Asymptomatic dermatophyte scalp carriage in school children in Erzincan, Turkey

AYDIN, Merve | GÜLHAN, Barış | GÜMRAL, Ramazan | İLKİT, Macit | ÖZTÜRK, Ali

Background: This study aimed to investigate the prevalence of symptomatic tinea capitis infections of the scalp and its asymptomatic carriage in students attending primary schools in Erzincan, Turkey. Materials and Methods: Eighteen primary schools were visited; 1 located in the central district and 17 located in other districts of the Erzincan province. From 2015 November to 2016 April, scalp scrapings were obtained from a total of 1879 students aged 6 to 13 years (mean age: 9.37±1.69) 924 (49.2%) male and 955 (50.8%) female using sterile hairbrushes, and assessed for tinea capitis and asympt ...Daha fazlası

Konferans Bildirisi 2018 Revista Română de Medicină de Laborator 3 Görüntülenme
Erişime Açık

Antifungal and anti-biofilm activity of new propane Sulfonyl Hydrazone Against Candida Isolates

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ummuhan

Candidiasis is the most frequently encountered fungal disease that ranges from mild mucosal infections to serious candidaemia and disseminated candidiasis. There are only limited classes of antifungal agents available for physicians to combat Candida infections. In addition, biofilm cells display phenotypic traits that resulting in enhanced resistance to antifungal drugs. Therefore, the limited option to combat fungal threat has raised the interest in seeking alternative antifungal compounds. The aim of this study was to investigate the antifungal and anti-biofilm activity of the new Sulfonyl ...Daha fazlası

Konferans Bildirisi 2019 5th International Congress on Applied Biological Sciences, Sarajevo-Bosnia&Herzegovina 4 Görüntülenme
Erişime Açık

Sıçanlarda Deneysel Olarak Oluşturulan Ülseratif Kolit Modelinde Farklı Tip Diyetlerle Beslenme ve Egzersizin Etkileri

ATEŞOĞLU, Rüstem | BAYIROĞLU, Fahri | KAYA, Mehmet Salih | ÇAYLI, Sevil | AKCAN, Gülben

AMAÇ: Ülseratif kolit (ÜK), kolon mukozasında gelişen kronik inflamatuvar gastrointestinal sistem hastalığıdır. Bağırsak dokusundaki inflamatuar cevabın bozulması, ÜK hastalığına yol açar. Egzersizin sebep olduğu anti-inflamatuar etki yoluyla kronik hastalıkların önlenebildiği veya etkisinin azaltılabildiği bilinmektedir. Buna karşın, egzersizin ÜK hastalığında muhtemel koruyucu etkisi ile farklı diyet alışkanlıklarının ÜK oluşumuna etkileri konusunda yeterli veri bulunmamaktadır. Bu çalışmada yüksek yağlı, proteinli ve karbonhidratlı diyetlerle birlikte yüzme egzersizinin ÜK gelişimi üzerine ...Daha fazlası

Konferans Bildirisi 2023 ACTA PHYSIOLOGICA 0 Görüntülenme
Erişime Açık

In Vitro Activity of Coenzymeq10 Loaded Mesoporous Silica Nanoparticles Against Mcf-7 Cells

GÜLBAHÇE MUTLU, Elif | ŞEFLEK, Hatice Nur | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur

Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası

Konferans Bildirisi 2023 İKİNCİ ULUSLARARASI SELÇUK SAĞLIK BİLİMLERİ KONGRESİ 1 Görüntülenme
Erişime Açık

Determination of Cytoxic Effects of Diazepam and Flumazenil in MCF-7 Cell Line

TÜRKOĞLU, Fatma Nur | ALPA, Şerife | GÜLBAHÇE MUTLU, Elif | ERBAYRAM, Fatma Zehra | ŞEFLEK, Hatice Nur

Background of the Study: Breast cancer, the second most common cause of cancer death, is a global public health problem due to its poor response to treatment and complex aetiology. The MCF-7 cell line is widely used in laboratories around the world for in vitro studies to address this problem. Diazepam is one of the most successful anaesthetics since the beginning of the psychopharmacological revolution. It belongs to a class of benzodiazepines that is often preferred in anaesthesia. Flumazenil is an imidazobenzodiazepine and was the first benzodiazepine antagonist to enter clinical use. The e ...Daha fazlası

Konferans Bildirisi 2023 Selçuk Üniversitesi 2 Görüntülenme
Erişime Açık

Determination Of Cytoxic Effects Of Oxytocin And Atosiban Mcf-7 Cell Line

ERBAYRAM, Fatma Zehra | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | TÜRKOĞLU, Fatma Nur | ŞEFLEK, Hatice Nur

Background of the Study: Breast cancer, a major cause of cancer-related deaths, is an important health problem due to its inadequate response to treatment and complex etiology. Oxytocin (OT) is a peptide mammalian hormone consisting of nine amino acids. Today, cellular studies of oxytocin have gained importance. Oxytocin has been observed to inhibit cell proliferation in cancer. The biggest advantage of oxytocin therapies is that they provide the organism with cell production on its own and have no side effects. Studies have shown that OT is a factor that stimulates cell proliferation in lung, ...Daha fazlası

Konferans Bildirisi 2023 Selçuk Üniversitesi 0 Görüntülenme
Erişime Açık

Determination of The Cytotoxic Effect of Propylthiouracil Loaded Mesoporous Silica on Mcf-7 Cell Line

GÜLBAHÇE MUTLU, Elif | ŞEFLEK, Hatice Nur | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur

Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası

Konferans Bildirisi 2023 SELÇUK ÜNİVERSİTESİ 0 Görüntülenme
Erişime Açık

Determination Of The Effect Of Coenzyme Q-10 On Spermatogenic Stem Cells By Immunohistochemistry Techniques In Male Rats With Experimental Hypothyroidism.

ŞEFLEK, Hatice Nur | ERBAYRAM, Fatma Zehra | CÜCE, Gökhan | KALKAN, Serpil

Deneysel Hipotiroidi Oluşturulan Erkek Ratlarda Koenzim Q10’un Spermatojenik Kök Hücrelere Etkisinin İmmünohistokimya Teknikleri İle BelirlenmesiIntroduction: Hypothyroidism is an endocrine disease that develops as a result of insufficient functioning of the thyroid gland. Hypothyroidism can cause male infertility by causing sexual dysfunction. Coenzyme Q10 (CoQ10) is widely used in the treatment of male infertility. CoQ10 can prevent abnormal sperm production at all stages of formation and maturation. In our study, the effect of CoQ10 on spermatogenic stem cells in rats with experimental ...Daha fazlası

Konferans Bildirisi 2023 0 Görüntülenme
Erişime Açık

Semen Microbiome Dysbiosis In Male Infertility

ŞEFLEK, Hatice Nur | ERBAYRAM, Fatma Zehra | TOKAK, Semik

Infertility is a major health problem and is increasing worldwide. The shift in the age at which both partners have their first child to older ages and lifestyle changes have contributed to the increase in the incidence of infertility. 50% of infertility in couples is due to male infertility. In vitro studies show that bacteria can negatively affect sperm function. Bacteria; has been shown to play an important role in many mechanisms that affect sperm function, including agglutination of motile sperm, induction of apoptosis, production of immobilization factors, and disruption of acrosome resp ...Daha fazlası

Konferans Bildirisi 2023 Harran Üniversitesi 0 Görüntülenme
Erişime Açık

The Effect Of Coenzyme Q10 Administration On The Expression Of Some Genes In Rats With Hypothroidia

ŞEFLEK, Hatice Nur | GÜLBAHÇE MUTLU, Elif | CÜCE, Gökhan | KALKAN, Serpil

Introduction: Hypothyroidism is an endocrine disorder that occurs mainly due to the insufficiency of thyroid hormones in the body or the inability of these hormones to affect target tissues. As a result of the insufficiency of thyroid hormones, the systems are affected and accordingly, the health status of individuals is adversely affected. Coenzyme Q10 is a lipophilic antioxidant that plays a role in membrane stability, energy conversion and ATP production. The aim of this study was to determine the effect of Coenzyme Q10 on GDNF, PLZF, SOX3 and THY1 gene expression levels in rats with hypoth ...Daha fazlası

Konferans Bildirisi 2023 SELÇUK ÜNİVERSİTESİ 0 Görüntülenme
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.
Tamam Açık Erişim PolitikasıAçık Erişim Yönergesi
creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms