- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır. - İptal tuşuna basarak normal aramaya dönebilirsiniz.
Mammary cancer, which is the second most common cause of cancer deaths, is one of the problems of global public health. It is argued that anti estrogenic agents such as melatonin will lead to a new aspect in treatment of breast cancer. In addition, zinc, which plays a crucial role in the etiology of cancer, is vital for many cellular processes, and an important trace mineral. Trace elements are regarded as multiple anti-cancer agents that regulate various biological mechanisms. METHODS: In this study, it was aimed to investigate the effects of melatonin and zinc application on lipid peroxidati ...Daha fazlası
The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası
ABSTRACT: The aim of the present was study determine the effects of zinc and melatonin on brain tissue (cortex) lipid peroxidation in rats with breast cancer induced by DMBA (7,12-Dimethylbenz[a]anthracene). Total 42 female wistar rats which was just weaned from milk equally separated 5 groups. Group 1 control, Group 2 DMBA control, Group 3 DMBA+ Zinc, Group 4 DMBA + Melatonin, Group 5 DMBA + Zinc +Melatonin. To induce breast cancer 80 mg/kg DMBA was given by gavage in colza oil (except group 1). Zinc and melatonin were supplemented as 5 mg/kg/day for 4 weeks. Brain tissue samples (cortex) wer ...Daha fazlası
The aim of the present was study determine the effect of zinc and melatonin supplementation on lipid peroxidation of various tissues in female rats with breast cancer induced by DMBA (7,12- Dimethylbenz[a]anthracene). Total 42 Wistar albino female rats were equally separated 5 groups. Group 1 control, Group 2 DMBA control, Group 3 DMBA+Zinc, Group 4 DMBA + Melatonin, Group 5 DMBA+Zinc+Melatonin. Lung, liver, spleen, pancreas and kidney tissue of rats were examined for MDA and GSH by spectrophotometric. The highest lung, liver, spleen, pancreas and kidney MDA levels were determined in group 2 ( ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.