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Atıf Dizini : Wos ✕İlgili Araştırmacılar : Kaniye Zeynep Çalışk ... ✕

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Arş.Gör. Kaniye Zeynep Çalışkan SakKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/FİZYOLOJİ ANABİLİM DALI/

Nadir Görülen Bir Vaka: Fanconi Aplastik Anemisi Gelişen Bir Klinefelter Sendromu Olgusu

TOKGÖZ, Hüseyin | ÇALIŞKAN, Ümran | DURAN, Tuğçe | ÇALIŞKAN SAK, Kaniye Zeynep

Giriş: Fankoni Aplastik Anemisi, çeşitli konjenital malformasyonlar, progresif pansitopeni ve genellikle hematolojik malignitelere yatkınlık ile karakterize genetik olarak çoğunlukla otozomal resesif olarak geçen bir hastalıktır. Konjenital anomaliler hastadan hastaya değişir ve başta iskelet malformasyonlarının yanı sıra ana organ sistemlerinden herhangi birini etkileyebilir. Klinefelter sendromu erkek hipogonadizminin en yaygın genetik formudur ve en sık görülen karyotip 47, XXY'dir. Vaka Sunumu: Halsizlik ve solukluk şikayetleri ile başvuran 9 yaşında erkek hastanın fizik muayenesinde kilo, ...Daha fazlası

Sunum 2022 KTO Karatay Üniversitesi Sağlık Bilimleri Dergisi 0 Görüntülenme

The Relationship Between Serum Asprosin Levels and Cardiovascular Risk Factors In Patients With Chronic Kidney Disease

TÜRKMEN, Kültigin | EROĞLU, Canan | ÇALIŞKAN SAK, Kaniye Zeynep | BALOĞLU, İsmail | KURAR, Ercan | KUTLU, Selim

Objective: The aim of this study was to determine serum asprosine levels in stage 3 and 4 chronic kidney disease (CKD) patients and healthy individuals and to investigate the relationship between this parameter and cardiovascular risk factors. Materials-Methods: In our investigation, serum and plasma samples from blood taken for standard laboratory testing were employed. In all, 91 people were involved in our investigation. Thirtyseven of these were patients with stage 3 CKD, twenty with stage 4 CKD, and 37 were healthy controls. Serum from both healthy and CKD participants was used to perform ...Daha fazlası

Sunum 2023 0 Görüntülenme

Effects of Mu Opioidergic Receptors on Endoplasmic Reticulum Stress in the Hypothalamus on Rats

ŞEN, Aysu | EROĞLU GÜNEŞ, Canan | ÇALIŞKAN SAK, Kaniye Zeynep | ERKAYA, Zeliha | DURSUN, Ebru Nur | KURAR, Ercan | KUTLU, Selim

AIM: Morphine, has strong analgesic effect as mu opioid receptor agonist. Naloxone is widely used as a general opioid receptorantagonist in many scientific researches. The effect of mu opioidergic effect on endoplasmic reticulum stress (ERS) in thehypothalamus is unknown. The aim of this study was to investigate the possible effects of morphine and naloxone on ERSmarkers in rat hypothalamus. METHODS: In the study, 24 young adult male Wistar albino rats were used. Animals were divided into 4 groups as control groupadministered wehicle for 5 days, morphine group administered 10mg/kg/day morphine ...Daha fazlası

Diğer 2023 0 Görüntülenme

Investigating thiol/disulfide homeostasis in acute migraine attack with aura

HORASANLI, Bahriye | AYDIN TERZİOĞLU, Merve | ŞUMLU, Esra | ÇALIŞKAN SAK, Kaniye Zeynep | ÖZŞAHİN, Aysun | FIRAT OĞUZ, Esra | EREL, Özcan

Aim: This study investigates thiol-disulfide hemostasis, which plays a role in the pathophysiology of migraine and is a new marker for oxidative stress in migraine with aura and healthy controls. Material and methods: The study included 53 healthy controls and 60 patients who presented to Konya City Hospital Neurology Outpatient Clinic with headache and were diagnosed migraine with aura. First, written informed consent was obtained from patients and controls. Then, dynamic thiol-disulfide homeostasis was investigated following the automated spectrophotometric method in serum samples of migrain ...Daha fazlası

Makale 2022 Ann Clin Anal Med 0 Görüntülenme

Serum YKL-40 (chitinase 3-like protein 1) levels in migraine patients during an attack

HORASANLI, Bahriye | ÇALIŞKAN SAK, Kaniye Zeynep | ÖZŞAHİN, Aysun | UÇAR KARABULUT, Keziban

Objectives: The aim of this study was to investigate YKL-40 in migraine patients during migraine attacks. Methods: In this prospective study, 30 migraine patients with aura (MWA) and 30 migraine patients without aura (MWOA) who presented to the Neurological Outpatient Department of Konya City Hospital during a migraine episode as well as 28 healthy controls were included. According to the manufacturer’s recommendations, serum YKL-40 levels were determined using an ELISA kit (FineTest). Statistical analysis of the data was performed with the IBM SPSS version 20.0 program. Results: The mean gend ...Daha fazlası

Makale 2023 Neurology Asia 5 Görüntülenme

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