The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor

YILMAZ, Seher | ALPA, Şerife | GÖÇMEN, Ayşe Yeşim | ÜLGER, Harun | ARSLAN, Esra | YAY, Arzu Hanım | ERTEKİN, Tolga | NİSARİ, Mehtap | YALÇIN, Betül

AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model developed in Balb/C type mice. METHODS: Ehrlich acid tumor (EAT) cells (1x106 EAT cell) from the stock animal were injected subcutaneously (s.c.) through the nape of the mice. Treatment groups of solid tumor-induced animals received 100 mg/kg and 200 mg/kg of C. mas L extract intraperitoneally (i.p.) for 14 days. RESULTS: Tumor volumes and animal weights were found to be stat ...Daha fazlası

Internal acoustic opening: Different osseous landmarks and their clinical implications

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife

ABSTRACT: Internal acoustic opening is a space that opens to facies posterior of the petrous piece of temporal bone that goes inside facial nerve, vestibulocochlear nerve, intermedial nevre and labyrinthine artery. The purpose of this study is the assessment of internal acoustic opening from a morphometric perspective, determination of the shape of the hole and determination of the distance to some important anatomic formations. This study is conducted on 166 temporal bones with unknown sex formation which are part of the skull collection in NEU and KTO Karatay University, Anatomy Department. ...Daha fazlası

Morphometric Evaluation of Rarely Seen Supratrochlear Foramen and Supracondylar Process in the Humerus in Turkish Population

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | TOKPINAR, Adem | UÇAR, Sümeyye | YILMAZ, Seher | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife

Abstract Background: Sometimes seen distal to humerus foramen supratrochleare and supracondylar process are rare variations. Supracondylar process is a variations observed on the distal side of humerus. The supracondylar process is a variant located 1/3 distal side of the humerus. The supratrochlear foramen may appear between the coronoid fossa and olecranon fossa. Since the foramen may appear in a semi-transparent form, it may be misdiagnosed as an osteolytic lesion. The aim of the present study was to identify the prevalence and morphology of supratrochlear foramen and the supracondylar proc ...Daha fazlası

A morphometric and morphological analysis of superior border of dry scapulae

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife | YILMAZ, Mehmet Tuğrul

Aim: The recognition of the scapula anatomy and visible variations is important in surgical treatments and arthroscopic procedures in case of any diseases of the shoulder. The morphological and morphometric characteristics of the scapular notch on the superior margin are very important. Because compression of the suprascapular nerve extending inside the scapular notch causes entrapment neuropathy. Therefore, the present study was planned in order to contribute to us as well as practitioners about morphometric and morphological characteristics of the superior margin of the scapula. Materials an ...Daha fazlası

Comparison of Upper Extremities of Children Who Playing and Not Playing Basketball. Turkish Journal of Sport and Exercise

ŞENER, Orhan Ahmet | ALPA, Şerife

In this study, it is aimed to compare the upper extremities of children who play and do not play basketball. In this study, measurements were taken in the upper extremities of a total of 200 secondary school students playing basketball and non-playing, with a mean age range of 11 ± 1.08 (did play sports) - 11 ± 0.8 (did not play sports). The average height and weight ratio of the students who did and did not play sports were 153.5 ± 12.9 - 149.2 ± 8.1 cm and 46.7 ± 12.04 - 43.08 ± 12.9 kg respectively. In the right and left upper extremities of the students who play sports, arm length was 28.4 ...Daha fazlası

Examining The Antitumoral Effect of Cornelian Cherry (Cornus Mas) in Ehrlich Ascites Tumor-Induced Mice

YILMAZ, Seher | ALPA, Şerife | NİSARİ, Mehtap | ŞEKER KARATOPRAK, Gökçe | ÜLGER, Harun | ERTEKİN, Tolga

Introduction: Different doses of C. Mas concentrated syrup on ascitic tumors was investigated in the Ehrlich Ascites Tumor model (EAT). Material and Methods: A total of 46 Balb/C mice were used in our study, 6 of which were stock animals and the other were in ascitic tumor groups. EAT cells (1x106 EAT cells) were injected intraperitoneally into all of the mice. Mice in the treatment groups with ascitic tumors received 100 mg/kg and 200 mg/kg Cornus Mas extract intraperitoneally for 9 days. Results: Counts after the 3 and 24-hour incubations in the EAT cell line that the average number of the d ...Daha fazlası

Investigating the anti-tumoral effect of curcumin on the mice inwhich Ehrlich ascites and solid tumor is created

YILMAZ, Seher | ÜLGER, Harun | ERTEKİN, Tolga | YAY, Arzu Hanım | NİSARİ, Mehtap | ALPA, Şerife | ACER, Niyazi

Volume estimation of the subcortical structuresin Parkinson’s disease using magnetic resonanceimaging: A methodological study

ERTEKİN, Tolga | ACER, Niyazi | İÇER, Semra | ALPA, Şerife

Determination of Antioxidant and Anticancer Activities of C. Sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadime | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası

Determination of Antioxidant and Anticancer Activities of C. sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadiem | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası