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Yazar/lar : ÖZDEMİR ÖZMEN, Ümmüh ... ✕İlgili Araştırmacılar : Merve Aydın Terzioğl ... ✕

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Doç. Dr. Merve Aydın TerzioğluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ MİKROBİYOLOJİ ANABİLİM DALI/

In vitro anti-candidal and anti-biofilm activity of new ethane sulfonyl hydrazone compound

ÖZTÜRK, Ali | AYDIN, Merve | ÖZDEMİR ÖZMEN, Ümmühan

Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. However, the emergence of resistance to the most common antifungal drugs, also due to biofilm formation, there is an increasing need to design new and more effective antifungals with less toxic. Sulfonyl hydrazones are well-known for their pharmacological effects, such as antifungal and antibacterial potential and can act as an antinociceptive, antidepressant, antineoplastic activity. The aim of this study was to investigate the anti-candidal and anti-biofilm activity o ...Daha fazlası

Konferans Bildirisi 2019 7 Görüntülenme

In vitro antifungal and antibiofilm activities of new butane sulfonyl hydrazone compound against medically important yeast

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan

The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası

Konferans Bildirisi 2019 11th Balkan Congress of Microbiology – Microbiologia Balkanica 2019, 6 Görüntülenme

Effect of New Sulfonyl Hydrazone Compounds Against Candida Biofilms

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZDEMİR ÖZMEN, Ümmühan | ŞUMLU, Esra

Objectives: Candidiasis is the most frequently encountered fungal infection, with ranges from mild superficial infections to disseminated candidiasis. Most manifestations of Candidiasis are associated with biofilm formation. Candida biofilms contributes to therapeutic failure due to resistance to antimicrobial agents and causes an increase in mortality rates. For these reasons, finding new drugs and antimicrobial agents are urgently needed. Sulfonyl hydrazones derived from sulfonamide, are well-known for its pharmacological effects, such as antifungal, antibacterial potential activity. This st ...Daha fazlası

Konferans Bildirisi 2021 The Seventh International Mediterranean Symposium on Medicinal and Aromatic Plants MESMAP – 7 0 Görüntülenme

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