The Effect of Zinc Deficiency and Supplementation on Elements in the Kidney Tissue of Ovariectomized Rats: Histopathologic Changes

BALTACI, Abdülkerim Kasım | SUNAR, Füsun | MOĞOLKOÇ, Rasim | TOY, Hatice

The objective of the present study is to determine the effects of zinc deficiency in and zinc supplementation to ovariectomized rats on some elements in kidney tissue. The study included 40 Sprague-Dawley type adult female rats. The experimental animals were randomized into four groups with equal numbers as follows: Group 1: Control (10). Group 2: Ovariectomized control (10). Group 3: Ovariectomized + zinc supplemented (10). Group 4: Ovariectomized + zinc deficient (10). After the animals were decapitated at the end of the experiment, element levels were determined by Atomic Emission (ICP-AES) ...Daha fazlası

Super Grandma, Active and Productive Women at 84 Years Operating in The Physiological Conditions of The Systems

SUNAR, Füsun | KOÇER, Bulent | ŞİMŞEK, Lütfi | ÇALIŞKAN, Kaniye Zeynep

Temperature measurements in a capacitive system of deep loco-regional hyperthermia.

ŞAHİNBAŞ, Hüseyin | ROSCH, Martin | DEMİRAY, Mutlu

Hyperthermia has been shown to be a medically useful procedure applicable for different indications. For the connection between clinical effects and heat, it is important to understand the actual temperatures achieved in the tissue. There are limited temperature data available when using capacitive hyperthermia devices even though this is worldwide the most widespread method for loco-regional heating. Hence, this study examines temperature measurements using capacitive heating. Bioequivalent phantoms were used for the measurements, which, however, do not consider perfusion in live tissue. In g ...Daha fazlası

A Realistic View on

BAHADORI, Fatemeh | DEMİRAY, Mutlu

The review paper entitled “The Essential Medicinal Chemistry of Curcumin”, published in the Journal of Medicinal Chemistry, by Nelson et al. (1) is a well-designed paper, presenting a new (and negative) approach to the well-known biologically active compound; curcumin. Although some arguments throughout this paper are completely true, the approach of the authors is unfortunately far from impartial, and many of the conclusions the authors draw from some of their referred papers are especially hard to accept.

Farmakogenetik Yönden Bireyler Arası Farmakokinetik Varyasyonlar

AL, Mevra | KILIÇ, Mehmet | ŞAHİN, Ayşe Saide | SONER, Burak Cem

Farmakogenetik (PGx), genetik varyasyonlar ve bunların bireyler arasında oluşturduğu ilaç yanıtı farklılıkları ile ilgilenir. İlaç metabolizmasından sorumlu enzimlerin keşfi ve bu enzimleri kodlayan DNA dizilimlerinin araştırılması bireysel tedavi stratejilerinin oluşturulmasını sağlar. İlaç metabolizmasından sorumlu sitokrom 2B6, sitokrom 2C9, sitokrom 2C19, sitokrom 2D6, sitokrom 3A4, N-asetil transferaz, dihidropirimidin dehidrogenaz, tiopurin metiltransferaz, 5’-difosfat (UDP)-glukuronoziltransferaz ve katekol-O-metil transferaz enzim polimorfizleri ilacın farmokokinetik özelliğini etkiley ...Daha fazlası

Thoracoscopic diaphragmatic plication with endostapler

ÖZKAN, Serdar

Diaphragma plication surgery is possibly the most advanced approach in terms of using different techniques. There are a number of plication and suturing methods, which are improved by transthoracic or thoracoscopic methods, and almost all of these techniques are still in use depending on an individual case or the status of diaphragm. We believe that the plication method using thoracoscopic methods and endostapler would be widely adopted as a safe technique. © 2017 All right reserved by the Turkish Society of Cardiovascular Surgery.