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Bulunan: 9 Adet 0.001 sn
Yayın Türü : Makale ✕Yazar/lar : GÜLBAHÇE MUTLU, Elif ... ✕
Koleksiyon [2]
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Yazar/lar [16]
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Konu Başlıkları [20]
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Erişime Açık

Comparative Analysis of Agronomic Traits and ISSR Method among Some Soybeans [Glycine Max (L.) Merr.] Genotypes

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif | DURSUN, Ömer | BAĞCI, Seydi Ahmet

In this study, the genetic diversity was investigated among 12 soybeans genotypes using inter simple sequence repeats (ISSR) and agronomic traits. DNA was isolated from the leaves of the genotypes. For molecular characterization, a total of 26 primers of ISSRs and eight agronomic characteristics were evaluated. ISSR analysis revealed 88 polymorphic bands. The genetic diversity among the genotypes according to ISSR analysis and agronomic traits were estimated based on Nei homology and Euclidian distance, respectively, and dendrograms reflecting genetic similarity were constructed using UPGMA an ...Daha fazlası

Makale 2020 KSU J. Agric Nat 4 Görüntülenme
Erişime Açık

The effects of aflatoxin B1 on growth hormone regulated gene-1 and interaction between DNA and aflatoxin B1 in broiler chickens during hatching

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ÖZNURLU, Yasemin | ÖZPARLAK, Haluk

Many types of aflatoxin cause problems for both public and animal health. Aflatoxin B1 (AFB1) is the most toxic and commonly encountered fungal toxin that appears in poultry feed and in feeds stored under unsuitable conditions. AFB1 decreases feed quality, egg production and fertility of hatching eggs. Also, AFB1 alters the development of embryos by infecting eggs. We investigated using sequence analysis the changes caused by different concentrations of AFB1 on the promoter sequences of the growth hormone regulated gene-1 (GHRG-1) in chick embryo at 13, 17, 19 and 21 days incubation. DNA isola ...Daha fazlası

Makale 2018 Biotechnic & Histochemistry 6 Görüntülenme
Erişime Açık

Genotyping of Staphylococcus Aureus Strains Isolated From Bovine Mastitis in Turkey by Using ERIC-PCR Method.

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Mastitis is an intramammary infection that leads to important economic losses in dairy industry such as increasing the amount of waste milk by affecting the quality and quantity of the milk, removing cows from herd or sending them for slaughter early. Staphylococcus aureus has an important place in the fight against mastitis. In this study, it is aimed to genotyping of the 98 S. aureus isolates that were isolated from bovine mastitis by the polymerase chain reaction of enterobacterial repetitive intergenic consensus (ERIC-PCR). ERIC primers generated DNA products in sizes ranging between ~8000 ...Daha fazlası

Makale 2016 Pakistan Journal of Zoology 6 Görüntülenme
Erişime Açık

The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

Makale 2020 3 Görüntülenme
Erişime Açık

DMBA ile meme kanseri oluşturulmuş sıçanlarda artan uterus doku hasarı çinko ve melatonin desteğiyle önlenir*

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra

Amaç: Bu çalışmanın amacı dişi sıçanlarda DMBA ile oluşturulmuş meme kanserinde çinko ile melatonin uygulamasının uterus dokusundaki lipit peroksidasyonu üzerine olan etkilerinin araştırılmasıdır. Gereç ve Yöntem: Wistar cinsi sütten yeni kesilmiş toplam 42 adet dişi sıçan kullanılan araştırmada hayvanlar 5 gruba ayrıldı: Grup 1 Kontrol, Grup 2 DMBA Kontrol, Grup 3 DMBA+Çinko, Grup 4 DMBA+Melatonin, Grup 5 DMBA+Melatonin ve Çinko. Grup 1 dışındaki hayvanlara meme kanseri oluşturmak için kolza yağı (kanola) içinde 80 mg/kg dozunda DMBA gavaj yoluyla verildi. Çinko ve melatonin uygulanan gruplar ...Daha fazlası

Makale 2020 Genel Tıp Dergisi 1 Görüntülenme
Erişime Açık

The Effect of Zinc and Melatonin Supplementation on Lipid Peroxidation of Various Tissues of Rats with by DMBA-Induced Breast Cancer

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra

The purpose of this study was to investigate the effects of zinc and melatonin administration on lipid peroxidation in various tissues in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups in the study: Group 1 (Control), Group 2 (DMBA Control), Group 3 (DMBA+Zinc), Group 4 (DMBA+Melatonin), Group 5 (DMBA+Melatonin, and Zinc). MDA (malondialdehyde) and GSH (glutathione) levels were determined via the spectrophotometric method in the lung, liver, spleen, pancreas, and kidney tissue samples taken from experimental animals. The highest ...Daha fazlası

Makale 2021 Biointerface Research 1 Görüntülenme
Erişime Açık

Zinc And Melatonin Supplementation Ameliorates Brain Cortex Tissue Damage in Dmba-Induced Breast Cancer İn Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra

BACKGROUND: This study aims to investigate the effects of zinc and melatonin supplementation on lipid peroxidation in the brain cortex in DMBA-induced breast cancer in female rats. METHODS: A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: Control (Group 1), DMBA Control (Group 2), DMBA+Zinc (Group 3), DMBA+Melatonin (Group 4), DMBA+Melatonin & Zinc (Group 5). At the end of the study, all animals were sacrifi ced by decapitation and Malondialdehyde (MDA) and glutathione (GSH) levels in brain cortex tissue samples were determined via spectrophotometric methods. RE ...Daha fazlası

Makale 2020 Bratisl Med J 3 Görüntülenme
Erişime Açık

Determination of Antioxidant and Anticancer Activities of C. Sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadime | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası

Makale 2023 Medical Records5 0 Görüntülenme
Erişime Açık

Determination of Antioxidant and Anticancer Activities of C. sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadiem | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası

Makale 2023 Medical Records - International Medical Journal 5 Görüntülenme
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