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Filtreler
Doç. Dr. Kamile YücelKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ BİYOKİMYA ANABİLİM DALI/
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Plasma Kallistatin Levels in Patients with COVID-19

YÜCEL, Kamile | YILDIZ, Salih | GÜRBÜZ, Ali Fuat

Purpose: The aim of this study was to evaluate kallistatin levels in patients diagnosed with COVID-19 and compare them with healthy controls. Materials and Methods: A total of 40 patients diagnosed with COVID-19, and 45 healthy controls were included in the study. The patient group was divided into 2 groups: patients treated in the service (n:20) and patients treated in the intensive care unit (n:20). Kallistatin levels were measured using the ELISA method. Results: There was a significant difference in kallistatin levels between the patient group (n:40) and the control group (n:45). There was ...Daha fazlası

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Comparison of Immunoassay and Liquid Chromatography-Tandem Mass Spectrometry Methods in the Measurement of Serum Androstenedione Levels.

YÜCEL, Kamile | ABUŞOĞLU, Sedat | ÜNLÜ, Ali

Abstract BACKGROUND: Recent reports have described inherent problems with androgen immunoassays compared with mass spectrometry analyses. In this study, a new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed according to CLSI rules. The developed method was compared with two immunoassay methods, the enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay (RIA). METHODS: After liquid-liquid extraction, a Shimadzu Prominence LC unit coupled to an ABSCIEX API 3200 mass spectrometer with atmospheric pressure chemical ionization was used to quantify serum andros ...Daha fazlası

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The Effect Of Serum And Follicular Fluid Hypoxia İnducible Factor 1α On İnvitro Fertilization Outcomes İn Patients With Polycystic Ovary Syndrome

YÜCEL, Kamile

Abstract Objective: To investigate serum and follicular fluid (FF) HIF-1α levels in nonobese, nonhyperandrogenic patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF), in addition to IVF outcomes. Materials and Methods: A prospective sequential cross-sectional study carried at a Research and Education Hospital. In total, 160 patients undergoing IVF treatment were included in the study: 80 patients diagnosed with PCOS according to the Rotterdam criteria (group I, study) and 80 patients with the etiology of male factor infertility (group II, control). Results: Th ...Daha fazlası

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Evaluation of University Students’ Nutritional Knowledge Attitudes and Behaviors

YÜCEL, Kamile

Objectives: In this study, nutritional habits of students, knowledge attitudes and behaviors about healthy nutrition will be evaluated. Materials and Methods: The sample comprised 818 students enrolled in the departments of the School of Health Sciences and the bachelor’s programs offered by the Faculty of Medicine. The developed data collection form consists of 52 questions. Results: In this study 818 (665 female, 153 male) students were reached. 22.3% of the students stated that smoke and 10.2% stated that used alcohol. The nutritional knowledge level was significantly higher in non-smokers, ...Daha fazlası

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Hypoxia induced factor-1a levels in patients undergoing adenoidectomy

YÜCEL, Kamile | AYDIN, İsa | ERDEM, Said Sami

Among the most common causes of nasal congestion in childhood is adenoid hypertrophy (AH) which leads to hypoxia. In this study, we studied plasma concentrations of hypoxia induced factor-1α (HIF-1α) in children undergoing adenoidectomy. The study included a total of 86 participants: 39 patients with AH and 47 healthy individuals. Serum HIF-1α levels (ng/mL) were measured by ELISA. HIF-1α concentrations were compared to the adenoid-nasopharyngeal ratio (ANR) of patients with AH, as recorded in the medical records. We found significantly higher concentrations of HIF-1α (0.30 ± 0.47 ng/mL) in pa ...Daha fazlası

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