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Arş.Gör. Kaniye Zeynep Çalışkan SakKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/FİZYOLOJİ ANABİLİM DALI/
Erişime Açık

The Relationship Between Serum Asprosin Levels and Cardiovascular Risk Factors In Patients With Chronic Kidney Disease

TÜRKMEN, Kültigin | EROĞLU, Canan | ÇALIŞKAN SAK, Kaniye Zeynep | BALOĞLU, İsmail | KURAR, Ercan | KUTLU, Selim

Objective: The aim of this study was to determine serum asprosine levels in stage 3 and 4 chronic kidney disease (CKD) patients and healthy individuals and to investigate the relationship between this parameter and cardiovascular risk factors. Materials-Methods: In our investigation, serum and plasma samples from blood taken for standard laboratory testing were employed. In all, 91 people were involved in our investigation. Thirtyseven of these were patients with stage 3 CKD, twenty with stage 4 CKD, and 37 were healthy controls. Serum from both healthy and CKD participants was used to perform ...Daha fazlası

Erişime Açık

In vitro effects of newly synthesized propane sulfonyl hydrazone derivatives on rat myometrial contractions

ŞUMLU, Esra | ÖZDEMİR ÖZMEN, Ummuhan | ÇALIŞKAN SAK, Kaniye Zeynep | YAVUZ, Ayça | BİLEN AYAN, Esra | KUTLU, Selim

This study aimed to investigate the potential of newly synthesized sulfonyl hydrazone (SH) derivatives to modulate contractions in isolated rat myometrium. For this purpose, the structures of SH compounds were characterized by elemental analyses and spectroscopic methods. Virgin female rats were obtained from KONUDAM Experimental Animal Research Centre (Konya, Turkey). Longitudinal myometrial strips, rapidly isolated post-decapitation, were rapidly inserted into a tissue bath containing Krebs' solution to monitor spontaneous contractions. Separate strips from each rat were treated with two dif ...Daha fazlası

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