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Ectopic Cushing's syndrome due to adrenocorticotropic hormone secreting atypical thymic carcinoid tumor.

DURAN, Cevdet | EREN KARANİS, Meryem İlkay | BAKDIK, Suleyman | ASLAN, Uysaler | ÇALIK, Mustafa | ÇALIK, Saniye Goknil

Cushing's syndromes (CS) due to thymic carcinoids are rarely seen. In this text, a case with CS due to ectopic adrenocorticotropic hormone (ACTH) secreting atypical thymic carcinoid tumor is presented. A 50-year-old Turkish male patient was admitted to our emergency department with typical CS features. Basal hormone profile, low- and high-dose dexamethasone suppression tests, and inferior petrosal sinus sampling results were consistent with ectopic ACTH secretion. Thorax computerized tomography showed an upper mediastinal mass, and trans-thoracic biopsy showed atypical thymic carcinoid with po ...Daha fazlası

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How successful is “pleural sound sign” in the identification of pneumothorax?

ÇALIK, Saniye Göknil | ÇALIK, Mustafa | GİRİŞKİN, Sadik | KARAOĞLAN, Osman | DÜNDAR, Zerrin Defne | ERGİN, Mehmet

OBJECTIVE: In the present study, in thorax ultrasonography (USG) Doppler images obtained from cases with occult pneumothorax, we investigated the status of pulsatile pleural sounds over the pleural line and called these as the pleural sound sign (PSS). The purpose of the present study was to identify the efficacy of the proposed PSS in diagnosing pneumothorax and to compare it with the other USG findings including the sliding lung sign (SLS) and seashore sign (SSS). METHODS: The present study included 66 consecutive patients who were referred to the emergency unit with a blunt trauma from Octo ...Daha fazlası

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Genitourinary Syndrome of Menopause: Effects on Related Factors, Quality of Life, and Self-care Power

KARAKOÇ, Hediye | KUL UÇTU, Arzu | ÖZERDOĞAN, Nebahat

INTRODUCTION: This study aimed to determine the effects of genitourinary syndrome of menopause on related factors, quality of life, and self-care power. MATERIAL AND METHODS: This case-control epidemiological study included 300 postmenopausal women aged 48-60 years who were divided into two groups: the case group (141) with genitourinary syndrome and the control group (159) without genitourinary syndrome. Data were evaluated by chi-square and t-tests in independent groups and logistic regression analysis. RESULTS: The incidence of genitourinary syndrome of menopause was 0.61 times higher in wo ...Daha fazlası

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Nurses' Information, Attıtude and Practices towards Use of Physical Restraint in Intensive Care Units.

BALCI, Hatice | ARSLAN, Selda

Introduction: Physical restraint may seem to be a useful and simple procedure to help the treatment but is a complex practice including physical, psychological, judicial, ethical and moral issues. Research was made on description basis in order to determine the knowledge, attitude and application levels of nurses working in critical care units about physical restraint applied on patients. Methods: The study was performed as a descriptive and correlation study. Working in ICUs, 158 nurses constituted the sampling. "Levels of Knowledge, Attitudes and Practices of Staff Regarding Physical Restrai ...Daha fazlası

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Relationship between generalized epileptic seizure and neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and neutrophil mediated inflammation.

GÜNEŞ, Muzaffer | BÜYÜKGÖL, Hüseyin

Aim: There is a close relationship between systemic inflammation and epileptic seizure. Recently, neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) have been defined as significant inflammation biomarkers. In the present study, it was aimed to determine levels of NLR, PLR, and mean platelet volume (MPV) during generalized tonic clonic epileptic seizures, and to investigate their relationships with epileptic seizures.Methods: The present study was conducted on 72 patients with epilepsy who applied with primary and secondary generalized tonic clonic epileptic seizures accordi ...Daha fazlası

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The Relationship of Ankyloglossia With Gender in Children and the Ideal Timing of Surgery in Ankyloglossia.

ATA, Nurdoğan | ALATAŞ, Necat | YILMAZ, Esra | ADAM, Ayşe Bülbül | GEZGİN, Bahri

Introduction: Ankyloglossia is a congenital condition that restricts tongue mobility. The aim of this study is to evaluate the relationship between gender and pediatric ankyloglossia and evaluate the planning of ideal timing of surgery. Methods: The files of pediatric patients in the Turkish population treated surgically for tongue-tie between June 2014 to June 2018 were scanned retrospectively. Results: Three hundred and eighty-two pediatric patients were included in the study. Of these, 115 (30.1%) were female and 267 (69.9%) were male. The prevalence of ankyloglossia was significantly highe ...Daha fazlası

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Evaluation of the Clinical Features, Management, and Prognoses of Patients With Charles Bonnet Syndrome.

BÜYÜKGÖL, Hüseyin | İLİK, Faik | ERTEM, Devrimsel Harika

Charles Bonnet syndrome (CBS) is characterized by visual hallucinations with preservation of cognitive abilities. The hallucinations consist mostly of vivid (realistic) objects and tend to reoccur. Here, we evaluate the etiologies, symptoms, treatments, and prognoses of 13 CBS cases. All patients had visual hallucinations but were normal on cognitive and psychiatric assessments. Patient demographic and clinical characteristics, treatment options, and 3-month follow-up data were retrospectively reviewed. The possible causes of CBS and what the patients perceived during their hallucinations were ...Daha fazlası

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MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing

MENGER, Marcus | YARMAN, Aysu | ERDŐSSY, Júlia | YILDIZ, Hüseyin Bekir | GYURCSÁNYI, Róbert Ervin | SCHELLER, Frieder Wolfram

Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides for the preparation of aptamers or total chemical synthesis for molecularly imprinted polymers (MIPs). The reproducible production of aptamers is a clear advantage, whilst the preparation of MIPs typically leads to a population of polymers with different binding sites. The realization of binding sites in the total bulk of the MIPs results in a higher binding capacity, however ...Daha fazlası

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Temperature measurements in a capacitive system of deep loco-regional hyperthermia.

ŞAHİNBAŞ, Hüseyin | ROSCH, Martin | DEMİRAY, Mutlu

Hyperthermia has been shown to be a medically useful procedure applicable for different indications. For the connection between clinical effects and heat, it is important to understand the actual temperatures achieved in the tissue. There are limited temperature data available when using capacitive hyperthermia devices even though this is worldwide the most widespread method for loco-regional heating. Hence, this study examines temperature measurements using capacitive heating. Bioequivalent phantoms were used for the measurements, which, however, do not consider perfusion in live tissue. In g ...Daha fazlası

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Folic-Acid-Modified Conducting Polymer: Electrochemical Detection of the Cell Attachment.

AZAK, Hacer | BARLAS, Fırat Barış | YILDIZ, Hüseyin Bekir | GÜLEÇ, Kadri | DEMİR, Bilal | ODACI DEMİRKOL, Dilek | TİMUR, Suna

Here, postfunctionalization and bioapplication of a π-conjugated polymer named 4-[4H-dithieno(3,2-b:2',3'-d)pyrrol-4-yl]aniline (DTP-aryl-NH2 ) are reported, which is successfully synthesized via electropolymerization onto the glassy carbon electrode. Folic acid (FA) is used to modify the amino functional polymer via N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide chemistry for the further steps. The selective adhesion of folate receptor positive cells on the surface is followed by the electrochemical methods. Cyclic voltammetry and electrochemical impedance s ...Daha fazlası

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A Realistic View on "The Essential Medicinal Chemistry of Curcumin".

BAHADORI, Fatemeh | DEMİRAY, Mutlu

The review paper entitled “The Essential Medicinal Chemistry of Curcumin”, published in the Journal of Medicinal Chemistry, by Nelson et al. (1) is a well-designed paper, presenting a new (and negative) approach to the well-known biologically active compound; curcumin. Although some arguments throughout this paper are completely true, the approach of the authors is unfortunately far from impartial, and many of the conclusions the authors draw from some of their referred papers are especially hard to accept.

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Comparison of rigid and semi-rigid instrumentation under acute load on vertebrae treated with posterior lumbar interbody fusion/transforaminal lumbar interbody fusion procedures: An experimental study.

ÖNEN, Mehmet Reşid | BAŞGÜL, Cemile | YILMAZ, İlhan | ÖZKAYA, Mustafa | DEMİR, Teyfik | NADERİ, Sait

Rigid and semi-rigid fixations are investigated several times in order to compare their biomechanical stability. Interbody fusion techniques are also preferable for maintaining the sagittal balance by protecting the disk height. In this study, the biomechanical comparison of semi-rigid and rigid fixations with posterior lumbar interbody fusion or transforaminal lumbar interbody fusion procedures is conducted under trauma. There were four different test groups to analyze the effect of acute load on treated ovine vertebrae. First and second groups were fixed with polyetheretherketone rods and tr ...Daha fazlası

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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