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Bulunan: 6 Adet 0.002 sn
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Filtreler
Filtreler
Bulunan: 6 Adet 0.002 sn
İlgili Araştırmacılar [5]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [2]
Yayın Tarihi [4]
Yayın Dili [2]
Erişime Açık

The Effect of Zinc Deficiency and Supplementation on Elements in the Kidney Tissue of Ovariectomized Rats: Histopathologic Changes

BALTACI, Abdülkerim Kasım | SUNAR, Füsun | MOĞOLKOÇ, Rasim | TOY, Hatice

The objective of the present study is to determine the effects of zinc deficiency in and zinc supplementation to ovariectomized rats on some elements in kidney tissue. The study included 40 Sprague-Dawley type adult female rats. The experimental animals were randomized into four groups with equal numbers as follows: Group 1: Control (10). Group 2: Ovariectomized control (10). Group 3: Ovariectomized + zinc supplemented (10). Group 4: Ovariectomized + zinc deficient (10). After the animals were decapitated at the end of the experiment, element levels were determined by Atomic Emission (ICP-AES) ...Daha fazlası

Erişime Açık

The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

Erişime Açık

Effect of 3’-4’-dihydroxyflavonol on lipid per oxidation inexperimental renal ischemia-reperfusion in rats

KOÇ, Aynur | ERGENE, Neyhan | BALTACI, Abdülkerim Kasım | MOĞULKOÇ, Rasim

This study aimed to examine the affects of 3’-4’-dihydroxyflavonol (DiOHF) on lipid peroxidation in experimental renal ischemia-reperfusion. The research was conducted on Wistar-albino type male rat. The experimental groups were formed as 1.Control; 2.Sham; 3.Ischemia; 4.Ischemia+reperfusion; 5.DiOHF+Ischemia; 6.Ischemia+ DiOHF + reperfusion. The highest tissue glutathione levels were found in groups 5 and 6. Groups 1 and 2, which were control and sham groups respectively, had the lowest tissue GSH values. Ischemia group was found to have the highest tissue malondialdehyde (MDA) level. Tissue ...Daha fazlası

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Zinc Ameliorates Nogo-A Receptor and Osteocalcin Gene Expression in Memory-Sensitive Rat Hippocampus Impaired by Intracerebroventricular Injection of Streptozotocin.

GÜMÜŞ, Haluk | BALTACI, Saltuk Buğra | ÜNAL, Ömer | GÜLBAHÇE-MUTLU Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Metabolic dysfunction is a critical step in the etiopathogenesis of Alzheimer's disease. In this progressive neurological disorder, impaired zinc homeostasis has a key role that needs to be clarified. The aim of this study was to investigate the effect of zinc deficiency and administration on hippocampal Nogo-A receptor and osteocalcin gene expression in rats injected with intracerebroventricular streptozotocin (icv-STZ). Forty male Wistar rats were divided into 5 groups in equal numbers: Sham 1 group received icv artificial cerebrospinal fluid (aCSF); Sham 2 group received icv a CSF and i.p. ...Daha fazlası

Erişime Açık

Marginal Maternal Zinc Deficiency Produces Liver Damage and Altered Zinc Transporter Expression in Offspring Male Rats.

GÜMÜŞ, Meltem | GÜLBAHÇE-MUTLU, Elif | ÜNAL, Ömer | BALTACI, Saltuk Buğra | ÜNLÜKAL, Nejat | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The aim of this study was to investigate how zinc deficiency and supplementation affect liver markers including autotaxin, kallistatin, endocan, and zinc carrier proteins ZIP14 and ZnT9 in rats exposed to maternal zinc deficiency. Additionally, the study aimed to assess liver tissue damage through histological examination. A total of forty male pups were included in the research, with thirty originating from mothers who were given a zinc-deficient diet (Groups 1, 2, and 3), and the remaining ten born to mothers fed a standard diet (Group 4). Subsequently, Group 1 was subjected to a zinc-defici ...Daha fazlası

Erişime Açık

The Effects Of Resveratrol And Melatonin On Biochemical And Molecular Parameters İn Diabetic Old Female Rat Hearts

AKGÜN-ÜNAL, Nilufer | ÖZYILDIIRM, Serhan | ÜNAL, Ömer | GÜLBAHEÇE-MUTLU, Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The roles of melatonin and resveratrol-enhanced activation of SIRT1 (silent information regulator 1), GLUT4 (glucose transporter type 4), and PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha) in mediating the protective effects on the heart in aged female rats with streptozotocin-induced diabetes were investigated. 16-month-old 48 Wistar female rats were separated into 8 groups with equal numbers. Group 1: Control, Group 2: Resveratrol Control, Group 3: Melatonin Control, Group 4: Resveratrol and Melatonin Control, Group 5: Diabetes, Group 6: Diabetes Resveratrol, G ...Daha fazlası

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