Crystallized phenol for sacral hidradenitis suppurativa

TURAN, Ersin | DOĞRU, Osman | KARGIN, Süleyman | KERİMOĞLU, Ramazan Saygın | NAZİK, Emet Ebru

Objective: Multiple treatment options for hidradenitis suppurativa (HS) have been suggested; none 100% successful. We assessed crystallized phenol treatment (CPT) for sacral HS. Methods: Twenty-five patients with sacral HS were enrolled. HS severity was assessed by Hurley Score and HS-Physician's Global Assessment (HS-PGA). All the leaking openings were dilated by a thin mosquito clamp after local anesthesia. Any hair present was removed, and phenol was applied. Results: Patients were followed-up for a mean 36.8 months. The mean number of CPT application was 3.98. After CPT mean Hurley score d ...Daha fazlası

Makale 2019 5 Görüntülenme

Effects Of Fentanyl On Pancreatic Cancer Cell Proliferation And Cancer Stem Cell Differentiation

ÇELİK, Feyzi | DURAN, Tuğçe

Pancreatic cancer is one of the most aggressive cancer due to the late diagnosis and failure to respond to the treatment despite advances in tumor biology and the development of new cancer therapeutic strategies. It has been reported that these characteristics of pancreatic cancer originate from cancer stem cells within the tumor mass. It has also been reported that Fentanyl is a fast-acting analgesic that binds to the mu-opioid receptors and some other mu-opioid receptors are involved in this cancer process. In this study, we determined the effect of Fentanyl on PANC-1 cells, by assessing the ...Daha fazlası

Makale 2019 10 Görüntülenme

Temperature measurements in a capacitive system of deep loco-regional hyperthermia.

ŞAHİNBAŞ, Hüseyin | ROSCH, Martin | DEMİRAY, Mutlu

Hyperthermia has been shown to be a medically useful procedure applicable for different indications. For the connection between clinical effects and heat, it is important to understand the actual temperatures achieved in the tissue. There are limited temperature data available when using capacitive hyperthermia devices even though this is worldwide the most widespread method for loco-regional heating. Hence, this study examines temperature measurements using capacitive heating. Bioequivalent phantoms were used for the measurements, which, however, do not consider perfusion in live tissue. In g ...Daha fazlası

Makale 2017 2 Görüntülenme

A Realistic View on

BAHADORI, Fatemeh | DEMİRAY, Mutlu

The review paper entitled “The Essential Medicinal Chemistry of Curcumin”, published in the Journal of Medicinal Chemistry, by Nelson et al. (1) is a well-designed paper, presenting a new (and negative) approach to the well-known biologically active compound; curcumin. Although some arguments throughout this paper are completely true, the approach of the authors is unfortunately far from impartial, and many of the conclusions the authors draw from some of their referred papers are especially hard to accept.

Makale 2017 5 Görüntülenme

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