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Bulunan: 79 Adet 0.001 sn
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Erişime Açık

The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor

YILMAZ, Seher | ALPA, Şerife | GÖÇMEN, Ayşe Yeşim | ÜLGER, Harun | ARSLAN, Esra | YAY, Arzu Hanım | ERTEKİN, Tolga | NİSARİ, Mehtap | YALÇIN, Betül

AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model developed in Balb/C type mice. METHODS: Ehrlich acid tumor (EAT) cells (1x106 EAT cell) from the stock animal were injected subcutaneously (s.c.) through the nape of the mice. Treatment groups of solid tumor-induced animals received 100 mg/kg and 200 mg/kg of C. mas L extract intraperitoneally (i.p.) for 14 days. RESULTS: Tumor volumes and animal weights were found to be stat ...Daha fazlası

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Utilization of Waste for Energy Generation in Clinker Production: Environmental Perspective

TUNÇEZ, Fatma Didem

Meeting the increasing energy need from fossil fuels such as coal, oil and natural gas caused the rapid depletion of natural resources. In a world where the need for energy is constantly increasing and resources are getting scarce, it is necessary to ensure the sustainability of energy. Clinker production is a process which require high amount of energy in manufacturing industry. The fact that energy is mostly obtained from coal, which is a non-renewable fuel, puts the future of the sustainability of cement production at risk. Alternative fuel usage plays the most important role in achieving m ...Daha fazlası

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Proanthocyanidins in grape seeds: An updated review of their health benefits and potential uses in the food industry

ÜNÜSAN, Nurhan

Grape seeds are rich sources of proanthocyanidins, which comprise polyhydroxyflavan oligomers or polymers. The beneficial health properties of grape seed proanthocyanidins are attributed to their conjugated and colonic metabolites. There is potential for a two-way relationship between the gut microbiota and grape seed proanthocyanidin. In particular, numerous in vitro and in vivo studies have demonstrated that grape seed proanthocyanidins appear to exert pharmacological effects. These include anti-oxidant, anti-microbial, anti-obesity, anti-diabetic, anti-neurodegenerative, anti-osteoarthritis ...Daha fazlası

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Water level change of lakes and sinkholes in Central Turkey under anthropogenic effects

DEMİR, Vahdettin | ÜLKE KESKİN, Aslı

Determining water level changes in lakes is significant for sustainable water supply planning, flood control, water resource management, and economic development with ecosystem sustainability. Trend analysis is a commonly used tool for detecting changes in hydrologic time series of quantities such as lake level, precipitation and temperature. Trend analysis of meteorological variables is very important for assessing the long-term changes in lake levels. This study examines long-term changes in the lakes in the Central Anatolia region of Turkey. Kızören and Timraş sinkhole lakes and Lakes Tuz a ...Daha fazlası

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İki Linkli Robot Manipülatörün Modellenmesi ve Bozucu Etki Altında Yörünge Kontrolü

İLGEN, Sinan | DURDU, Akif | GÜLBAHÇE, Erdi | ÇAKAN, Abdullah

Bu çalışmada, iki linkli düzlemsel bir robot manipülatörün bozucu etki altında yörünge kontrolü yapılmıştır. ADAMS yazılımı vasıtasıyla manipülatörün sanal bir prototipi oluşturulmuştur. Ayrıca, sistem için gerekli olan kontrolcü tasarımı MATLAB/Simulink ortamında gerçekleştirilmiştir. Sistemin simülasyonu ise MATLAB ve ADAMS yazılımlarının eş zamanlı olarak çalıştırılması ile gerçekleştirilmiştir. Robot manipülatör iki giriş ve dört çıkışa sahiptir. Girişler, her iki eklemin tahriki için gerekli olan motor torkları, çıkışlar ise her iki eklemin açıları ve uç elemanın konumunun x-y bileşenleri ...Daha fazlası

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Trend Analyses of Meteorological Variables and Lake Levels for Two Shallow Lakes in Central Turkey

YAĞBASAN, Özlem | DEMİR, Vahdettin | YAZICIGİL, Hasan

Trend analyses of meteorological variables play an important role in assessing the long-term changes in water levels for sustainable management of shallow lakes that are extremely vulnerable to climatic variations. Lake Mogan and Lake Eymir are shallow lakes offering aesthetic, recreational, and ecological resources. Trend analyses of monthly water levels and meteorological variables affecting lake levels were done by the Mann-Kendall (MK), Modified Mann-Kendall (MMK), Sen Trend (ST), and Linear trend (LT) methods. Trend analyses of monthly lake levels for both lakes revealed an increasing tre ...Daha fazlası

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The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

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Survey on the User Satisfaction with the Mass Housing Projects Led by District Municipality: Konya-Karatay Example

HATİPOĞLU ŞAHİN, Betül | TERECİ, Ayşegül

Mass housing played an important role in changing the face of the cities. The Municipality Law No.5393 which gave the right to municipalities to build mass housing were factors that have accelerated the mass housing production. The main goal of local administrations is to build houses in the most rapid and economic way for group of people with low income. However, such production has posed problems in terms of quantity and quality. This research has been conducted to measure the satisfaction levels of users from mass housing projects which are implemented under the leadership of the municipali ...Daha fazlası

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Prediction and sensitivity analysis under different performance indices of R1234ze ORC with Taguchi’s multi-objective optimization

ATA, Sadık | KAHRAMAN, Ali | ŞAHİN, Remzi

In this study, parametric optimization and sensitivity analysis of performance parameters were performed for the Organic Rankine Cycle (ORC) system at 120 °C heat source temperature. R1234ze, which is called the new-generation fluid, was used in the ORC design. Performance parameters have been selected considering Energy, Exergy, Economy (Turbine performance) and Environmental (Thermodynamic sustainability indices) factors. Six performance indices used in the orthogonal design with Taguchi-ANOVA. These are; thermal efficiency, turbine power, exergy efficiency, total irreversibility, Volume Flo ...Daha fazlası

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The effects of pelvic floor muscle training combined with Kinesio taping on bladder symptoms, pelvic floor muscle strength, and quality of life in women with overactive bladder syndrome: A randomized sham-controlled trial

TOPRAK ÇELENAY, Şeyda | KORKUT, Zehra | OSKAY, Kemal | AYDIN, Arif

ABSTRACT Background: There is insufficient study using Kinesio taping (KT) in bladder problems. Objectives: To investigate the effects of pelvic floor muscle training (PFMT) combined with KT on bladder symptoms, pelvic floor muscle strength, and quality of life in women with overactive bladder (OAB) syndrome and compare this combination with PFMT plus sham tape (ST). Methods: Women with OAB were randomly allocated into PFMT+KT and PFMT+ST groups. All patients were given PFMT for 6 weeks and applied taping according to groups. Before and after treatment, the OAB symptoms with the Overactive Bla ...Daha fazlası

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Production and properties of phase separated porous glass

ERTUŞ, Emre Burak | AHMETOĞLU, Çekdar Vakıf | ÖZTÜRK, Abdullah

A sodium borosilicate glass (SBG) was produced by conventional melt-quenching. As cast glass was heat treated to induce phase separation (SBG-HT), followed by acid leaching with HCl to dissolve one of the separated phases; i.e. alkali rich borate phase, so that a porous glass (PG) was obtained. In order to alter the pore structure, produced PG was subsequently alkali (NaOH) leached or alternatively heat treated. The samples were characterized by techniques including XRD, SEM, N2 adsorption/desorption. The total pore volume for PG was found to be 0.314 cm3/g, reached to 0.370 cm3/g by alkali le ...Daha fazlası

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Pion–kaon femtoscopy and the lifetime of the hadronic phase in Pb−Pb collisions at √ sNN = 2.76 TeV

KARASU UYSAL, Ayben | ALICE Collaboration

In this paper, the first femtoscopic analysis of pion–kaon correlations at the LHC is reported. The analysis was performed on the Pb–Pb collision data at √sNN = 2.76 TeV recorded with the ALICE detector. The non-identical particle correlations probe the spatio-temporal separation between sources of different particle species as well as the average source size of the emitting system. The sizes of the pion and kaon sources increase with centrality, and pions are emitted closer to the centre of the system and/or later than kaons. This is naturally expected in a system with strong radial flow and ...Daha fazlası

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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