The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor

YILMAZ, Seher | ALPA, Şerife | GÖÇMEN, Ayşe Yeşim | ÜLGER, Harun | ARSLAN, Esra | YAY, Arzu Hanım | ERTEKİN, Tolga | NİSARİ, Mehtap | YALÇIN, Betül

AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model developed in Balb/C type mice. METHODS: Ehrlich acid tumor (EAT) cells (1x106 EAT cell) from the stock animal were injected subcutaneously (s.c.) through the nape of the mice. Treatment groups of solid tumor-induced animals received 100 mg/kg and 200 mg/kg of C. mas L extract intraperitoneally (i.p.) for 14 days. RESULTS: Tumor volumes and animal weights were found to be stat ...Daha fazlası

Optimal Residential Load Control Comparison Using Linear Programming and Simulated Annealing for Energy Scheduling

GÜLER, Emre | BAŞARAN FİLİK, Ümmühan

Many tariffs are used for electricity pricing. Electricity bills can be reduced by choosing the optimal working hours of appliances and for appropriate tariffs in smart homes. In this study, Linear Programming (LP) and Simulated Annealing (SA) methods are realized and compared each other to find minimum bill. The multi-time tariffs that have different energy unit prices at different times of the day are preferred. Energy Management System (EMS) shifts time slots of some appliances to cheap energy unit prices. Optimal load control is applied to prevent high peak demand because there may be over ...Daha fazlası

Utilization of Waste for Energy Generation in Clinker Production: Environmental Perspective

TUNÇEZ, Fatma Didem

Meeting the increasing energy need from fossil fuels such as coal, oil and natural gas caused the rapid depletion of natural resources. In a world where the need for energy is constantly increasing and resources are getting scarce, it is necessary to ensure the sustainability of energy. Clinker production is a process which require high amount of energy in manufacturing industry. The fact that energy is mostly obtained from coal, which is a non-renewable fuel, puts the future of the sustainability of cement production at risk. Alternative fuel usage plays the most important role in achieving m ...Daha fazlası

Fluoroscopy-guided genicular nerves pulsed radiofrequency for chronic knee pain treatment

ARICAN, Şule | HACIBEYOĞLU, Gülçin | AKKOYUN SERT, Özlem | TUNCER UZUN, Sema | REİSLİ, Ruhiye

Objectives: The primary objective of this study was to investigate the effects of Pulsed RF application in the genicular nerve on pain and function in patients with osteoarthritis (OA) and its side effects. Methods: This study was conducted between February 2018 and June 2018. Patients who were previously administered diagnostic blocks were evaluated a day later; a drop of at least 50% in numeric pain scores was considered a positive response, and these patients were included in the Pulsed RF neurotomy procedures. Radiofrequency (RF) cannula was advanced towards targeted nerves under the guida ...Daha fazlası

Comparative Analysis of Agronomic Traits and ISSR Method among Some Soybeans [Glycine Max (L.) Merr.] Genotypes

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif | DURSUN, Ömer | BAĞCI, Seydi Ahmet

In this study, the genetic diversity was investigated among 12 soybeans genotypes using inter simple sequence repeats (ISSR) and agronomic traits. DNA was isolated from the leaves of the genotypes. For molecular characterization, a total of 26 primers of ISSRs and eight agronomic characteristics were evaluated. ISSR analysis revealed 88 polymorphic bands. The genetic diversity among the genotypes according to ISSR analysis and agronomic traits were estimated based on Nei homology and Euclidian distance, respectively, and dendrograms reflecting genetic similarity were constructed using UPGMA an ...Daha fazlası

Proanthocyanidins in grape seeds: An updated review of their health benefits and potential uses in the food industry

ÜNÜSAN, Nurhan

Grape seeds are rich sources of proanthocyanidins, which comprise polyhydroxyflavan oligomers or polymers. The beneficial health properties of grape seed proanthocyanidins are attributed to their conjugated and colonic metabolites. There is potential for a two-way relationship between the gut microbiota and grape seed proanthocyanidin. In particular, numerous in vitro and in vivo studies have demonstrated that grape seed proanthocyanidins appear to exert pharmacological effects. These include anti-oxidant, anti-microbial, anti-obesity, anti-diabetic, anti-neurodegenerative, anti-osteoarthritis ...Daha fazlası

The Discharge Related Learning Needs Of Hematopoietic Stem Cell Transplant Recipients

İSTER, Emine Derya | KAPLAN SERİN, Emine | BAYIR, Berna | ERKURT, Mehmet Ali

This study has been carried out to determine the learning needs of patients undergoing hematopoietic stem cell transplantation at the discharge stage. 100 patients undergoing transplantation in the Stem Cell Transplantation Unit of a university hospital in Turkey in 2018 have constituted the sample of the study. The "Patient Information Form" and the "Patient Learning Needs Scale" have been used as data collection tools in the study. In the study, the data have been collected 2-48 hours before the patients were discharged. The mean total score of the Patient Learning Needs Scale of the patient ...Daha fazlası

Water level change of lakes and sinkholes in Central Turkey under anthropogenic effects

DEMİR, Vahdettin | ÜLKE KESKİN, Aslı

Determining water level changes in lakes is significant for sustainable water supply planning, flood control, water resource management, and economic development with ecosystem sustainability. Trend analysis is a commonly used tool for detecting changes in hydrologic time series of quantities such as lake level, precipitation and temperature. Trend analysis of meteorological variables is very important for assessing the long-term changes in lake levels. This study examines long-term changes in the lakes in the Central Anatolia region of Turkey. Kızören and Timraş sinkhole lakes and Lakes Tuz a ...Daha fazlası

The Effect of the Education Model on the Levels of State/Continuous Anxiety and Self‑Efficacy of Midwifery Students

Background: In midwifery practice, the education model used for skill acquisition is extremely important for the management of students’ stress, anxiety and self‑efficacy. Innovative practices aim to improve the students’ cognitive, emotional and psychomotor skills, and new research needs to be performed to evaluate the results of such practices. Aims: The present study aimed to evaluate the effects of the education model and clinical practice features, such as practice time, laboratory practice and exam evaluation, on the students’ state and continuous anxiety and self‑efficacy status. Method ...Daha fazlası

Pre-Service Teachers’ Cognition on Student Understanding in the EFL Language Classroom

ÇELİK, Mehmet | KORKUT, Perihan

The way language teachers respond to learners’ failure to internalize language may considerably vary. Some teachers may prioritize making the language in their classrooms understood in its entirety, contrary to their teacher education in which roughly-tuned input is advised rather than finely-tuned input. Considering that teachers’ practices are often influenced by their cognitions, this study set out to uncover teacher cognitions on student understanding during their teacher education. The participants were 13 pre-service EFL teachers doing their practicum at high schools in Turkey. Participa ...Daha fazlası

Investigation Of Applications Of Fibonacci Sequence And Golden Ratio In Music

BAKIM, Sümeyye | YÖRE, Seyit

In studies presented in the literature, relationships between music and mathematics can sometimes be observed. Leonardo Fibonacci (1170-1250) is well known in mathematics with the Fibonacci Sequence and this sequence used to identify numbers in various music elements, too. In related studies, these numbers have been used to demonstrate the existence of the ‘Golden Ratio’ using methods and theories borrowed from the components of music. Nevertheless, this relationship has subsequently been seen inaccurate. The studies that previously based some works of Chopin, Mozart, Beethoven, Bach and Bartó ...Daha fazlası

Change of Bedroom and Fixed Furnitures in Apartment Buildings in Konya From Early Republic of Turkey to the Present

HATİPOĞLU ŞAHİN, Betül | DAĞ GÜRCAN, Ayşenur

Housing emerges as an architectural product provides to individuals needs such as shelter, rest, nutrition, social and economic. Development process of the housing is affected in social factors such as culture, privacy, social events, economic condition, lifestyle, as well as environmental factors such as topography, climate, wind, sun, direction. In our country, especially with the effect of the Industrial Revolution, the participation of women in business life has changed the family structure. Large family structure evolved into nuclear families has also been an important factor in shaping t ...Daha fazlası