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Manyetik Rezonans Görüntüleme Rehberliğinde Fokus Ultrason ile Talamotominin Esansiyel Tremor Tedavisindeki Yeri

ÖZTÜRK, Gülşah | AKPINAR, Elif | ŞENCAN, Fahir | SARICA, Can

Yaklaşık 100 yıldır tremor tedavisinde fonksiyonel nöroşirürjiye başvurulmaktadır. Lezyon cerrahisi ve derin beyin stimülasyonu, esansiyel tremor hastalığında etkinliği kanıtlanmış tedavi yöntemleridir. Son zamanlarda kullanımı giderek artan diğer bir tedavi yöntemi ise; düşük yan etki profili ile genel anestezi ve insizyon ihtiyacı olmadan uygulanan "Manyetik Görüntüleme Rehberliğinde Fokus Ultrason'dur (MRgFUS)." Bu tedavi ile yer ve ısı tayini yapılarak yaklaşık 1 mm hata payı ile talamusta 2-6 mm çapında lezyon oluşturulabilmektedir. Yazıda, MRgFUS'un geçtiğimiz yıllarda Amerikan Gıda ve İ ...Daha fazlası

Makale 2018 4 Görüntülenme

Effects of curcumin on methyl methanesulfonate damage to mouse kidney

CÜCE, Gökhan | ÇETİNKAYA, Seda | İŞİTEZ, Nilay | KÜÇÇÜKTÜRK, Serkan | SÖZEN, Mehmet Enes | DEMİREL, Hasan Hüseyin | KALKAN, Sinan | CİĞERCİ, İbrahim Hakkı

Methylmethane sulfonate (MMS) is an alkylating agent that may react with DNA and damage it. We investigated histological changes and apoptosis caused by MMS and the effects of curcumin on MMS treated mouse kidneys. Twenty-four mice were divided into four equal groups: controls injected with saline, a group injected with 40 mg/kg MMS, a group injected with 40 mg/kg MMS and given 100 mg/kg curcumin by gavage, and a group given 100 mg/kg curcumin by gavage. MMS caused congestion and vacuole formation, and elevated the apoptotic index significantly, but had no other effect on kidney tissue. Curcum ...Daha fazlası

Makale 2016 6 Görüntülenme

Emergence of rotavirus G9 in 2012, as the dominant genotype in Turkish children with diarrhea, in a university hospital in Ankara

ALTAY KOÇAK, Aylin | AYDIN TERZİOĞLU, Merve | MATSUMOTO, Takashi | YAHIRO, Takaaki | DALGIÇ, Buket | BOZDAYI, Gülendam | AHMET, Kamruddin

http://hdl.handle.net/20.500.12498/4422

Makale 2019 UNIV PRESS 8 Görüntülenme

Randomized prospective comparison of long-term results of onlay and sublay mesh repair techniques for incisional hernia

SEVİNÇ, Barış | OKUŞ, Ahmet | AY, Serden | AKSOY, Nergis | KARAHAN, Ömer

Objective: Incisional hernia is a significant problem after laparotomy, and there is still no consensus on an ideal treatment method. The aim of this study was to compare the results of onlay and sublay mesh repair techniques. Material and Methods: In this randomized prospective trial, 100 patients were divided into two groups: Onlay and sublay groups. Recurrences were evaluated by performing a physical examination. Results: The median follow-up was 37.1 (26.6 to 46.5) months. In the onlay group, the mean operation time was significantly shorter. However, in terms of postoperative pain and wou ...Daha fazlası

Makale 2018 AVES İbrahim KARA 1 Görüntülenme

The effect of smartphone usage on the median nerve

İLİK, Faik | BÜYÜKGÖL, Hüseyin | EREN, Fatma | İLİK, Mustafa Kemal | KAYHAN, Fatih | KÖSE, Hatice

Purpose: The aim of this study was to examine the effects of smartphone use on the median nerve. Materials and Methods: Participants were classified into three groups according to their smartphone use frequencies, high smartphone users (with Smartphone addiction scale (SAS) score of higher than 71), low smartphone users (SAS score less than 71) and classical type mobile phones users. The Visual analogue scale (VAS), quick-disabilities of arm, shoulder, hand (qDASH) and median nerve conductions of the participants were assessed. Groups were compared to each other as well as dominant and non-dom ...Daha fazlası

Makale 2018 CUKUROVA UNIV, FAC MEDICINE 1 Görüntülenme

Temperature measurements in a capacitive system of deep loco-regional hyperthermia.

ŞAHİNBAŞ, Hüseyin | ROSCH, Martin | DEMİRAY, Mutlu

Hyperthermia has been shown to be a medically useful procedure applicable for different indications. For the connection between clinical effects and heat, it is important to understand the actual temperatures achieved in the tissue. There are limited temperature data available when using capacitive hyperthermia devices even though this is worldwide the most widespread method for loco-regional heating. Hence, this study examines temperature measurements using capacitive heating. Bioequivalent phantoms were used for the measurements, which, however, do not consider perfusion in live tissue. In g ...Daha fazlası

Makale 2017 2 Görüntülenme

The validity of eight neoclassical facial canons in the Turkish adults

KARACA SAYGILI, Ömür | ÇINAR, Selçuk | GÜLCEN, Burak | ÖZCAN, Emrah | KUŞ, İlter

The neoclassical canons were used to define the proportions between various areas of the head and face. Therefore, this study was done to establish the neoclassical canons of facial proportions in Turkish adults. A total of 200 healthy adults 20 to 35 years of age were examined. Using anthropometric landmarks, 5 horizontal and 9 vertical direct measurements were made on the faces with a sliding calliper. Results have been compared with 8 neoclassical facial canons. When comparing between sexes, a significant difference has been found in all measurements except the upper facial width, left eye- ...Daha fazlası

Makale 2016 Via Medica 10 Görüntülenme

A Realistic View on

BAHADORI, Fatemeh | DEMİRAY, Mutlu

The review paper entitled “The Essential Medicinal Chemistry of Curcumin”, published in the Journal of Medicinal Chemistry, by Nelson et al. (1) is a well-designed paper, presenting a new (and negative) approach to the well-known biologically active compound; curcumin. Although some arguments throughout this paper are completely true, the approach of the authors is unfortunately far from impartial, and many of the conclusions the authors draw from some of their referred papers are especially hard to accept.

Makale 2017 5 Görüntülenme

Farmakogenetik Yönden Bireyler Arası Farmakokinetik Varyasyonlar

AL, Mevra | KILIÇ, Mehmet | ŞAHİN, Ayşe Saide | SONER, Burak Cem

Farmakogenetik (PGx), genetik varyasyonlar ve bunların bireyler arasında oluşturduğu ilaç yanıtı farklılıkları ile ilgilenir. İlaç metabolizmasından sorumlu enzimlerin keşfi ve bu enzimleri kodlayan DNA dizilimlerinin araştırılması bireysel tedavi stratejilerinin oluşturulmasını sağlar. İlaç metabolizmasından sorumlu sitokrom 2B6, sitokrom 2C9, sitokrom 2C19, sitokrom 2D6, sitokrom 3A4, N-asetil transferaz, dihidropirimidin dehidrogenaz, tiopurin metiltransferaz, 5’-difosfat (UDP)-glukuronoziltransferaz ve katekol-O-metil transferaz enzim polimorfizleri ilacın farmokokinetik özelliğini etkiley ...Daha fazlası

Makale 2017 Selçuk Tıp Dergisi 7 Görüntülenme

An anatomic study of the lateral femoral cutaneous nerve in human fetuses

FAZLIOĞULLARI, Zeliha | UYSAL, İsmihan İlknur | DOĞAN, Nadire Ünver | KARABULUT, Ahmet Kağan | ZİYLAN, Taner

Objectives: The aim of the study was to determine the anatomic course of the lateral femoral cutaneous nerve (LFCN) and its branches in relation to certain anatomic landmarks in human fetuses. Methods: This study was performed on 50 thighs from 25 spontaneously aborted fetuses with no detectable malformations. The LFCN position was evaluated according to its relation to the anterior superior iliac spine and its distance from the femoral nerve and femoral artery were measured along the inguinal ligament (IL). The relationship between the LFCN and femoral nerve in the pelvic cavity was also eval ...Daha fazlası

Makale 2016 4 Görüntülenme

Hastane Çalışanlarının İş Sağlığı ve Güvenliği

SUNAR, Füsun | ÇINAR, Şerife

Sağlık sektörü yoğun emek isteyen sektörlerden birisidir. Doktorlar, eczacılar, diş hekimleri, veterinerler, mühendisler, işletmeciler, temizlik ve bakım işçileri, sosyal hizmet uzmanları, diyet ve beslenme uzmanları, hemşireler, ebeler, şoförler ve hatta aşçılar sağlık çalışanlarının içindedirler. Bugünkü geniş kapsamlı iş sağlığı anlayışı, çalışanların iyilik haline, iş doyumuna ve yaşam kalitesine kadar uzanan geniş bir disiplindir. Sağlık çalışanları da bu disiplin içerisinde yer alır. Hastaneler, İş Sağlığı ve Güvenliği’ne İlişkin İşyeri Tehlike Sınıfları Tebliği’ne göre “Çok tehlikeli iş ...Daha fazlası

Makale 2017 STED 6 Görüntülenme

The Effect of Zinc Deficiency and Supplementation on Elements in the Kidney Tissue of Ovariectomized Rats: Histopathologic Changes

BALTACI, Abdülkerim Kasım | SUNAR, Füsun | MOĞOLKOÇ, Rasim | TOY, Hatice

The objective of the present study is to determine the effects of zinc deficiency in and zinc supplementation to ovariectomized rats on some elements in kidney tissue. The study included 40 Sprague-Dawley type adult female rats. The experimental animals were randomized into four groups with equal numbers as follows: Group 1: Control (10). Group 2: Ovariectomized control (10). Group 3: Ovariectomized + zinc supplemented (10). Group 4: Ovariectomized + zinc deficient (10). After the animals were decapitated at the end of the experiment, element levels were determined by Atomic Emission (ICP-AES) ...Daha fazlası

Makale 2017 INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH 3 Görüntülenme

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