[email protected] Karatay
    • Türkçe
    • English
  • English 
    • Türkçe
    • English
  • Login
View Item 
  •   [email protected] Karatay
  • ARAŞTIRMA ÇIKTILARI
  • Scopus İndeksli Yayınlar Koleksiyonu
  • View Item
  •   [email protected] Karatay
  • ARAŞTIRMA ÇIKTILARI
  • Scopus İndeksli Yayınlar Koleksiyonu
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Electrochemical glucose biosensing via new generation DTP type conducting polymers/gold nanoparticles/glucose oxidase modified electrodes

Azak, H.; Kurbanoglu, S.; Yildiz, H.B.; Ozkan, S.A.
  • BibTex
  • EndNote (RIS)
Loading
Thumbnail
Date
2016
URI
http://hdl.handle.net/20.500.12498/3022
Metadata
Show full item record
Abstract
The synthesis of derivatives of dithionepyrrole is a hot subject that has been studied extensively. In this study, a novel approach for constructing different glucose biosensors using conducting polymers of 4-(4H-dithyinol[3,2-b:2′,3′-d]pyroll-4-yl)aniline and 4-(4H-dithyinol[3,2-b:2′,3′-d]pyroll-4-yl)-[1,1′-biphenyl]-4-amine is proposed. After the synthesis and characterizations of the dithionepyrrole type monomers, they were used in glucose biosensing applications. The surface of gold electrodde was modified with mercaptoethane sulfonic acid and p-aminothiophenol functionalized gold nanoparticles and aniline modified GOx. Electrochemical measurements were carried out by following the consumed oxygen due to the enzymatic reaction of glucose oxidase. DTP-Ph-NH2/AuNP/GOx and DTP-Ph-Ph-NH2/AuNP/GOx biosensors showed very good linearity between 0.1 and 2.5 mM, and 0.05 and 1 mM for glucose, respectively. LOD value was obtained for pDTP-Ph-NH2/AuNP/GOx as 5.00 × 10− 2 mM and for pDTP-Ph-Ph-NH2/AuNP/GOx as 9.86 × 10− 5 mM using S/N ratio. Optimization of molar ratio amount of AuNP/GOx, cycles amount to immobilize AuNP/GOx, conducting polymer thickness were examined. Finally, under optimized conditions, the amount of glucose in spiked human serum samples and recovery experiments were conducted. © 2016 Elsevier B.V....  Show more  Show less
Item type
Article
Collections
  • Scopus İndeksli Yayınlar Koleksiyonu [475]

- KTO Karatay Kutuphanesi
- KTO Karatay Universitesi
- Contact Us / Send Feedback
DSpace software
Gemini
 

 

Browse

Communities & CollectionsBy Issue DateAuthorsTitlesSubjectsBy lcAuthorBy TypeBy publisherBy languageBy rightsThis CollectionBy Issue DateAuthorsTitlesSubjectsBy lcAuthorBy TypeBy publisherBy languageBy rights

My Account

LoginRegister

- KTO Karatay Kutuphanesi
- KTO Karatay Universitesi
- Contact Us / Send Feedback
DSpace software
Gemini