Comparison of Ankaferd Blood Stopper and silver sulfadiazine use in burn wounds: An experimental study

Abstract

BACKGROUND: The present study was designed to compare the effectiveness of topical silver sulfadiazine (SSD) and Ankaferd Blood Stopper (R) (ABS) usage in experimental partial-thickness burns in rats. METHODS: Twenty-one male Wistar albino rats weighing 250-290 (range: 270 +/- 19) g were used in the present study. A round brass probe that was specifically designed (3x3 cm diameter) was used to induce the burns in rats. After the presence of partial-thickness burns was confirmed, the rats were divided into three groups: Group 1 (ABS group) Ankaferd Blood Stopper (R) pad, Group 2 (SSD group) silver sulfadiazine (Silverdin (R)), and Group 3 (Control group) 1\% isotonic saline solution-impregnated pad. The healing period was followed up clinically and histopathologically. The day on which 50\% and 80\% of re-epithelization at first were detected for each rat was also recorded. RESULTS: The mean times of 50\% and 80\% of re-epithelization at first were 10.8 days, 13.8 days, and 16.8 days in Groups 1, 2, and 3, respectively (p<0.001), and 16.4 days, 19.7 days, and 25.2 days, respectively (p<0.001). The mean inflammatory scores were also found to be better in the ABS group than in other groups (p<0.05). CONCLUSION: Our study showed that ABS has better results for the healing of the burn wound than SSD in experimental partial-thickness burns in rats.