Nodular Splenic Sarcoidosis: A Rare Case Report

Sarcoidosis is an idiopathic, multi-systemic, granulomatous disease. It most commonly involves the lungs. Herein, we present a rare and usually asymptomatic case with splenic sarcoidosis without liver involvement. A 31-year-old male patient was admitted to our clinic with cough, sputum, and shortness of breath. He reported no common systemic complaints of sarcoidosis. Thoracic and abdominal computed tomography showed multiple hypodense mediastinal lymph nodes with splenic involvement. No other intra-abdominal pathology or peripheral lymphadenopathy was detected. Mediastinoscopy was performed. Diagnosis was made histopathologically. Following the treatment, his complaints regressed. Nodular splenic involvements are uncommon. Although there have been reported thirty-nine cases of sarcoidosis with multiple nodular hepatic and splenic lesions, only three isolated splenic cases have been reported in the literature to date. Despite its rarity, extra-pulmonary sarcoidosis may cause significant morbidity and mortality. Therefore, we discuss this case to draw attention to splenic sarcoidosis without liver involvement and its manifestations, diagnosis, and clinical course.