Detaylı Arama
İptal
Bulunan: 136 Adet 0.010 sn
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Filtreler
Filtreler
Bulunan: 136 Adet 0.010 sn
Koleksiyon : Tıp Fakültesi ✕
Koleksiyon [2]
İlgili Araştırmacılar [20]
Ambargo Durumu [2]
Tam Metin [2]
Yayın Türü [5]
Yazar/lar [20]
Atıf Dizini [8]
Konu Başlıkları [20]
Yayıncı [20]
Tez Danışmanı [8]
Dergi Adı [4]
Yayın Tarihi [10]
Dergi Sayısı [3]
Yayın Dili [3]
dc.description.provenance [20]
Erişime Açık

Borrelia burgdorferi chemotaxis toward tick protein Salp12 contributes to acquisition

MURFIN, Kristen E. | KELINBARD, Ruby | AYDIN, Merve | SALAZAR, Samuel A. | FIKRIG, Erol

Lyme disease is a common tick-borne infection caused by the spirochete Borrelia burgdorferi sensu stricto (s.s.). B. burgdorferi s.s. may utilize chemotaxis, the directional migration towards or away from a chemical stimulus, for transmission, acquisition, and infection. However, the specific signals recognized by the spirochete for these events have not been defined. In this study, we identify an Ixodes scapularis salivary gland protein, Salp12, that is a chemoattractant for the spirochete. We demonstrate that Salp12 is expressed in the I. scapularis salivary glands and midgut and expression ...Daha fazlası

Makale 2019 Ticks and Tick-borne Disease 5 Görüntülenme
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Effect of 3’-4’-dihydroxyflavonol on lipid per oxidation inexperimental renal ischemia-reperfusion in rats

KOÇ, Aynur | ERGENE, Neyhan | BALTACI, Abdülkerim Kasım | MOĞULKOÇ, Rasim

This study aimed to examine the affects of 3’-4’-dihydroxyflavonol (DiOHF) on lipid peroxidation in experimental renal ischemia-reperfusion. The research was conducted on Wistar-albino type male rat. The experimental groups were formed as 1.Control; 2.Sham; 3.Ischemia; 4.Ischemia+reperfusion; 5.DiOHF+Ischemia; 6.Ischemia+ DiOHF + reperfusion. The highest tissue glutathione levels were found in groups 5 and 6. Groups 1 and 2, which were control and sham groups respectively, had the lowest tissue GSH values. Ischemia group was found to have the highest tissue malondialdehyde (MDA) level. Tissue ...Daha fazlası

Makale 2019 Pakistan Journal of Pharmaceutical Sciences 3 Görüntülenme
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Morphometric Evaluation of Rarely Seen Supratrochlear Foramen and Supracondylar Process in the Humerus in Turkish Population

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | TOKPINAR, Adem | UÇAR, Sümeyye | YILMAZ, Seher | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife

Abstract Background: Sometimes seen distal to humerus foramen supratrochleare and supracondylar process are rare variations. Supracondylar process is a variations observed on the distal side of humerus. The supracondylar process is a variant located 1/3 distal side of the humerus. The supratrochlear foramen may appear between the coronoid fossa and olecranon fossa. Since the foramen may appear in a semi-transparent form, it may be misdiagnosed as an osteolytic lesion. The aim of the present study was to identify the prevalence and morphology of supratrochlear foramen and the supracondylar proc ...Daha fazlası

Makale 2022 Harran Üniversitesi Tıp Fakültesi Dergisi 3 Görüntülenme
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A morphometric and morphological analysis of superior border of dry scapulae

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife | YILMAZ, Mehmet Tuğrul

Aim: The recognition of the scapula anatomy and visible variations is important in surgical treatments and arthroscopic procedures in case of any diseases of the shoulder. The morphological and morphometric characteristics of the scapular notch on the superior margin are very important. Because compression of the suprascapular nerve extending inside the scapular notch causes entrapment neuropathy. Therefore, the present study was planned in order to contribute to us as well as practitioners about morphometric and morphological characteristics of the superior margin of the scapula. Materials an ...Daha fazlası

Makale 2023 Medical Records 6 Görüntülenme
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In vitro anti-candidal and anti-biofilm activity of new ethane sulfonyl hydrazone compound

ÖZTÜRK, Ali | AYDIN, Merve | ÖZDEMİR ÖZMEN, Ümmühan

Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. However, the emergence of resistance to the most common antifungal drugs, also due to biofilm formation, there is an increasing need to design new and more effective antifungals with less toxic. Sulfonyl hydrazones are well-known for their pharmacological effects, such as antifungal and antibacterial potential and can act as an antinociceptive, antidepressant, antineoplastic activity. The aim of this study was to investigate the anti-candidal and anti-biofilm activity o ...Daha fazlası

Konferans Bildirisi 2019 7 Görüntülenme
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Gebelerdeki Asemptomatik Bakteriüri: Sıklığı, Antimikrobiyal Duyarlılık Profili, Etken Mikroorganizmalar ve Risk Faktörleri

TOKAK, Semih | ERİÇ HORASANLI, Jule

Asemptomatik bakteriüri (ASB) idrar yolu infeksiyonlarının belirgin belirtileri olmadan idrarda bakteri varlığı olarak tanımlanmaktadır. Asemptomatik bakteriüri hamilelik sırasında ortaya çıkmakta olup hamilelik sırasında tedavi edilmediğinde olumsuz maternal ve perinatal sonuçlarla ilişkilendirilmektedir. Bu çalışmadaki amacımız bölgemizde kadın hastalıkları ve doğum kliniğine başvuran gebelerdeki ASB görülme sıklığını, ilişkili risk faktörlerini, bakteriüriye sebep olan mikroorganizmaları ve antibiyotik duyarlılıklarını belirlemektir. Üniversite hastanemizin kadın hastalıkları ve doğum klini ...Daha fazlası

Makale 2020 Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 7 Görüntülenme
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Erişkin Yoğun Bakım Ünitesinde Yatan Hastalarda Kandidemi Risk Faktörlerinin Belirlenmesi

TOKAK, Semih | UĞURCAN, Doğaç | TEKİNDAL, Mustafa Agah

Sağlık hizmeti ile ilişkili infeksiyonlar içinde önemli bir grubu mantar infeksiyonları oluşturmaktadır. Mantar infeksiyonları arasında en sık olarak Candida türleri izole edilmektedir. Candida türleri Amerika Birleşik Devletleri’nde dördüncü sırada yer alan hastane kaynaklı infeksiyon etkenidir. Bu çalışma ile yetişkin hastalardaki kandidemi risk faktörleri, Candida tür dağılımı ve antifungal duyarlılıklarının belirlenmesi amaçlanmıştır. Bu olgu-kontrol çalışmasında Ocak 2016-Ocak 2017 tarihleri arasında elde edilen veriler retrospektif olarak değerlendirildi. Hastalara ait demografik özellik ...Daha fazlası

Makale 2020 Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 1 Görüntülenme
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In vitro antifungal and antibiofilm activities of new butane sulfonyl hydrazone compound against medically important yeast

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan

The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası

Konferans Bildirisi 2019 11th Balkan Congress of Microbiology – Microbiologia Balkanica 2019, 6 Görüntülenme
Erişime Açık

Examining The Antitumoral Effect of Cornelian Cherry (Cornus Mas) in Ehrlich Ascites Tumor-Induced Mice

YILMAZ, Seher | ALPA, Şerife | NİSARİ, Mehtap | ŞEKER KARATOPRAK, Gökçe | ÜLGER, Harun | ERTEKİN, Tolga

Introduction: Different doses of C. Mas concentrated syrup on ascitic tumors was investigated in the Ehrlich Ascites Tumor model (EAT). Material and Methods: A total of 46 Balb/C mice were used in our study, 6 of which were stock animals and the other were in ascitic tumor groups. EAT cells (1x106 EAT cells) were injected intraperitoneally into all of the mice. Mice in the treatment groups with ascitic tumors received 100 mg/kg and 200 mg/kg Cornus Mas extract intraperitoneally for 9 days. Results: Counts after the 3 and 24-hour incubations in the EAT cell line that the average number of the d ...Daha fazlası

Makale 2019 8 Görüntülenme
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Asymptomatic dermatophyte scalp carriage in school children in Erzincan, Turkey

AYDIN, Merve | GÜLHAN, Barış | GÜMRAL, Ramazan | İLKİT, Macit | ÖZTÜRK, Ali

Background: This study aimed to investigate the prevalence of symptomatic tinea capitis infections of the scalp and its asymptomatic carriage in students attending primary schools in Erzincan, Turkey. Materials and Methods: Eighteen primary schools were visited; 1 located in the central district and 17 located in other districts of the Erzincan province. From 2015 November to 2016 April, scalp scrapings were obtained from a total of 1879 students aged 6 to 13 years (mean age: 9.37±1.69) 924 (49.2%) male and 955 (50.8%) female using sterile hairbrushes, and assessed for tinea capitis and asympt ...Daha fazlası

Konferans Bildirisi 2018 Revista Română de Medicină de Laborator 3 Görüntülenme
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Asymmetrical Dimethylarginine Levels in Hepatitis B Virus-Positive Patients

KARAKEÇİLİ, Faruk | ÇIKMAN, Aytekin | AYDIN, Merve | GÜLHAN, Barış

BACKGROUND: High asymmetrical dimethylarginine (ADMA) levels have been associated with endothelial dysfunction and contribute to the development of several diseases. However, data on the relationship between hepatitis B virus (HBV) and ADMA are limited. The aim of our study was to explore the relationship between ADMA and HBV by comparing the ADMA levels in patients with chronic active hepatitis B (CHB), inactive HBV carriers (carriers), and healthy volunteers (controls). METHODS: The participants were divided into three groups: 90 patients with CHB, 90 HBV carriers, and 90 controls. Serum ADM ...Daha fazlası

Makale 2018 Annals of Laboratory Medicine 4 Görüntülenme
Erişime Açık

Geographical Features and Seroprevalence of Borrelia burgdorferi in Erzincan, Turkey

ÇIKMAN, Aytekin | AYDIN, Merve | GÜLHAN, Barış | KARAKEÇİLİ, Faruk | DEMİRTAŞ, Levent | KESİK, Ozan Arif

Background: We aimed to determine the geographical features and seroprevalence of Borrelia burgdorferi in Erzincan, Turkey, which has a high tick population due to its geographical position and climatic conditions. Methods: From January to December 2014, 368 people living in Erzincan, northeastern Turkey were enrolled. B. burgdorferi IgG antibodies were investigated in the collected serum samples using the ELISA method in 2015. Positive and borderline results were confirmed using the Western Blot (WB) method. Results: Borrelia burgdorferi IgG positivity was found to be 4.1% by ELISA and 2.17% ...Daha fazlası

Makale 2018 Journal of Arthropod-Borne Diseases 3 Görüntülenme
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