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Bulunan: 9 Adet 0.001 sn
Atıf Dizini : Scopus ✕İlgili Araştırmacılar : Elif Gülbahçe Mutlu ... ✕
Koleksiyon [2]
İlgili Araştırmacılar [13]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [3]
Yazar/lar [20]
Atıf Dizini [4]
Konu Başlıkları [20]
Yayıncı [5]
Dergi Adı [1]
Yayın Tarihi [5]
Yayın Dili [2]
dc.description.provenance [4]
Dr. Öğr. Üyesi Elif Gülbahçe MutluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ BİYOLOJİ ANABİLİM DALI/
Erişime Açık

The effects of aflatoxin B1 on growth hormone regulated gene-1 and interaction between DNA and aflatoxin B1 in broiler chickens during hatching

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ÖZNURLU, Yasemin | ÖZPARLAK, Haluk

Many types of aflatoxin cause problems for both public and animal health. Aflatoxin B1 (AFB1) is the most toxic and commonly encountered fungal toxin that appears in poultry feed and in feeds stored under unsuitable conditions. AFB1 decreases feed quality, egg production and fertility of hatching eggs. Also, AFB1 alters the development of embryos by infecting eggs. We investigated using sequence analysis the changes caused by different concentrations of AFB1 on the promoter sequences of the growth hormone regulated gene-1 (GHRG-1) in chick embryo at 13, 17, 19 and 21 days incubation. DNA isola ...Daha fazlası

Makale 2018 Biotechnic & Histochemistry 6 Görüntülenme
Erişime Açık

Genotyping of Staphylococcus Aureus Strains Isolated From Bovine Mastitis in Turkey by Using ERIC-PCR Method.

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Mastitis is an intramammary infection that leads to important economic losses in dairy industry such as increasing the amount of waste milk by affecting the quality and quantity of the milk, removing cows from herd or sending them for slaughter early. Staphylococcus aureus has an important place in the fight against mastitis. In this study, it is aimed to genotyping of the 98 S. aureus isolates that were isolated from bovine mastitis by the polymerase chain reaction of enterobacterial repetitive intergenic consensus (ERIC-PCR). ERIC primers generated DNA products in sizes ranging between ~8000 ...Daha fazlası

Makale 2016 Pakistan Journal of Zoology 6 Görüntülenme
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The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

Makale 2020 3 Görüntülenme
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The Effect of Zinc and Melatonin Supplementation on Lipid Peroxidation of Various Tissues of Rats with by DMBA-Induced Breast Cancer

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra

The purpose of this study was to investigate the effects of zinc and melatonin administration on lipid peroxidation in various tissues in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups in the study: Group 1 (Control), Group 2 (DMBA Control), Group 3 (DMBA+Zinc), Group 4 (DMBA+Melatonin), Group 5 (DMBA+Melatonin, and Zinc). MDA (malondialdehyde) and GSH (glutathione) levels were determined via the spectrophotometric method in the lung, liver, spleen, pancreas, and kidney tissue samples taken from experimental animals. The highest ...Daha fazlası

Makale 2021 Biointerface Research 1 Görüntülenme
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Zinc And Melatonin Supplementation Ameliorates Brain Cortex Tissue Damage in Dmba-Induced Breast Cancer İn Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra

BACKGROUND: This study aims to investigate the effects of zinc and melatonin supplementation on lipid peroxidation in the brain cortex in DMBA-induced breast cancer in female rats. METHODS: A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: Control (Group 1), DMBA Control (Group 2), DMBA+Zinc (Group 3), DMBA+Melatonin (Group 4), DMBA+Melatonin & Zinc (Group 5). At the end of the study, all animals were sacrifi ced by decapitation and Malondialdehyde (MDA) and glutathione (GSH) levels in brain cortex tissue samples were determined via spectrophotometric methods. RE ...Daha fazlası

Makale 2020 Bratisl Med J 3 Görüntülenme
Erişime Açık

In Vitro Activity of Coenzymeq10 Loaded Mesoporous Silica Nanoparticles Against Mcf-7 Cells

GÜLBAHÇE MUTLU, Elif | ŞEFLEK, Hatice Nur | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur

Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası

Konferans Bildirisi 2023 İKİNCİ ULUSLARARASI SELÇUK SAĞLIK BİLİMLERİ KONGRESİ 1 Görüntülenme
Erişime Açık

Zinc Ameliorates Nogo-A Receptor and Osteocalcin Gene Expression in Memory-Sensitive Rat Hippocampus Impaired by Intracerebroventricular Injection of Streptozotocin.

GÜMÜŞ, Haluk | BALTACI, Saltuk Buğra | ÜNAL, Ömer | GÜLBAHÇE-MUTLU Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Metabolic dysfunction is a critical step in the etiopathogenesis of Alzheimer's disease. In this progressive neurological disorder, impaired zinc homeostasis has a key role that needs to be clarified. The aim of this study was to investigate the effect of zinc deficiency and administration on hippocampal Nogo-A receptor and osteocalcin gene expression in rats injected with intracerebroventricular streptozotocin (icv-STZ). Forty male Wistar rats were divided into 5 groups in equal numbers: Sham 1 group received icv artificial cerebrospinal fluid (aCSF); Sham 2 group received icv a CSF and i.p. ...Daha fazlası

Makale 2023 0 Görüntülenme
Erişime Açık

Marginal Maternal Zinc Deficiency Produces Liver Damage and Altered Zinc Transporter Expression in Offspring Male Rats.

GÜMÜŞ, Meltem | GÜLBAHÇE-MUTLU, Elif | ÜNAL, Ömer | BALTACI, Saltuk Buğra | ÜNLÜKAL, Nejat | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The aim of this study was to investigate how zinc deficiency and supplementation affect liver markers including autotaxin, kallistatin, endocan, and zinc carrier proteins ZIP14 and ZnT9 in rats exposed to maternal zinc deficiency. Additionally, the study aimed to assess liver tissue damage through histological examination. A total of forty male pups were included in the research, with thirty originating from mothers who were given a zinc-deficient diet (Groups 1, 2, and 3), and the remaining ten born to mothers fed a standard diet (Group 4). Subsequently, Group 1 was subjected to a zinc-defici ...Daha fazlası

Diğer 2023 0 Görüntülenme
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The Effects Of Resveratrol And Melatonin On Biochemical And Molecular Parameters İn Diabetic Old Female Rat Hearts

AKGÜN-ÜNAL, Nilufer | ÖZYILDIIRM, Serhan | ÜNAL, Ömer | GÜLBAHEÇE-MUTLU, Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The roles of melatonin and resveratrol-enhanced activation of SIRT1 (silent information regulator 1), GLUT4 (glucose transporter type 4), and PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha) in mediating the protective effects on the heart in aged female rats with streptozotocin-induced diabetes were investigated. 16-month-old 48 Wistar female rats were separated into 8 groups with equal numbers. Group 1: Control, Group 2: Resveratrol Control, Group 3: Melatonin Control, Group 4: Resveratrol and Melatonin Control, Group 5: Diabetes, Group 6: Diabetes Resveratrol, G ...Daha fazlası

Makale 2023 0 Görüntülenme
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