Detaylı Arama
İptal
Bulunan: 10 Adet 0.002 sn
- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır.
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Filtreler
Filtreler
Bulunan: 10 Adet 0.002 sn
Yayın Dili : en ✕Yazar/lar : BALTACI, Abdülkerim ... ✕
Koleksiyon [2]
İlgili Araştırmacılar [10]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [3]
Yazar/lar [12]
Atıf Dizini [3]
Konu Başlıkları [20]
Yayıncı [6]
Yayın Tarihi [4]
Yayın Dili [1]
Erişime Açık

The Effect of Zinc Deficiency and Supplementation on Elements in the Kidney Tissue of Ovariectomized Rats: Histopathologic Changes

BALTACI, Abdülkerim Kasım | SUNAR, Füsun | MOĞOLKOÇ, Rasim | TOY, Hatice

The objective of the present study is to determine the effects of zinc deficiency in and zinc supplementation to ovariectomized rats on some elements in kidney tissue. The study included 40 Sprague-Dawley type adult female rats. The experimental animals were randomized into four groups with equal numbers as follows: Group 1: Control (10). Group 2: Ovariectomized control (10). Group 3: Ovariectomized + zinc supplemented (10). Group 4: Ovariectomized + zinc deficient (10). After the animals were decapitated at the end of the experiment, element levels were determined by Atomic Emission (ICP-AES) ...Daha fazlası

Makale 2017 INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH 3 Görüntülenme
Erişime Açık

The Effect of Melatonin and Zinc Application in Rats Induced Mammary Carcinoma with DMBA on Lipid Peroxidation

GÜLBAHÇE MUTLU, Elif | MENEVŞE, Esma | BALTACI, Abdülkerim Kasım | MOĞULKOÇ, Rasim

Mammary cancer, which is the second most common cause of cancer deaths, is one of the problems of global public health. It is argued that anti estrogenic agents such as melatonin will lead to a new aspect in treatment of breast cancer. In addition, zinc, which plays a crucial role in the etiology of cancer, is vital for many cellular processes, and an important trace mineral. Trace elements are regarded as multiple anti-cancer agents that regulate various biological mechanisms. METHODS: In this study, it was aimed to investigate the effects of melatonin and zinc application on lipid peroxidati ...Daha fazlası

Konferans Bildirisi 2017 International INES Academic Researches Congress 6 Görüntülenme
Erişime Açık

The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

Makale 2020 3 Görüntülenme
Erişime Açık

The Effects of Resveratrol Supplementation on Oxidant Stress in Old Female Rats with Induced Diabetes

ATACAK, Adem | GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | ÜNAL, Ömer | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Bu çalışmanın amacı diyabet oluşturulmuş yaşlı dişi sıçan modelinde resveratrol desteğinin retinal doku hasarını nasıl etkilediğini araştırmaktır. Bu çalışma Selçuk Üniversitesi Deneysel Tıp Araştırma ve Uygulama Merkezinden temin edilen Wistar cinsi 24 adet erişkin yaşlı dişi sıçan (16 haftalık) üzerinde aynı merkezde gerçekleştirildi. Çalışma protokolü Selçuk Üniversitesi Deneysel Tıp Araştırma ve Uygulama Merkezi Deney Hayvanları Etik Kurulu tarafından onaylandı. Toplam 24 adet yaşlı dişi sıçan kullanılan araştırmada gruplar şu şekilde oluşturuldu: Grup 1. Kontrol, Grup 2. Kontrol + resvera ...Daha fazlası

Konferans Bildirisi 2019 International Congress of Science, Culture and Education 4 Görüntülenme
Erişime Açık

Cerebral Ischemia Reperfusion Injury in Rats: Effect of 3’,4’-Dihydroxyflavonol

MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım | MENEVŞE, Esma | BALTACI, Saltuk Buğra | GÜLBAHÇE MUTLU, Elif

The aim of present study was to determine the effect of 3',4'-dihydroxyflavonol (DiOHF) on experimental brain ischemia-reperfusion in rats. The study was performed on the 34 male Wistar-albino rats, weigth 350-400 gr. Experiment groups were designed as 1-Sham; 2-Ischemia-reperfusion; 3-DiOHF+Ischemiareperfusion; 4-Ischemia+DiOHF+Reperfusion; 5- Ischemia-reperfusion+DiOHF. DiOHF was given to animals as 10 mg/kg by intraperitoneal. Cerebral cortex was analyzed for malondyaldehyde (MDA), NO (nitric oxide), xanthine oxidase (XO), glutathione (GSH) and glutathione peroxidase (GPx). Tissue MDA level ...Daha fazlası

Konferans Bildirisi 2018 Internatıonal Academic Research Congress (INES-2018) 7 Görüntülenme
Erişime Açık

Effect of Chronic Running Exercise in Experimental Diabetes Mellitus Rat Model on Lipid Peroxidation in the Hippocampus

YAŞLI, Mehmet | BALTACI, Saltuk Buğra | AKGÜN ÜNAL, Nilüfer | GÜLBAHÇE MUTLU, Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Introduction and Objectives: The aim of this study is to investigate the effect of the chronic running exercise in diabetic rats on lipid peroxidation in hippocampus tissue. The study was carried out in Experimental Medicine Research and Application Center of Selçuk University on adult male Wistar rats that were obtained from the same center. The study protocol was approved by the Ethics Committee of Experimental Animals of Experimental Medicine Research and Application Center of Selcuk University. Methods: A total of 40 rats were equally divided into 4 groups: Group 1, Control, Group 2, Exerc ...Daha fazlası

Sunum 2019 17th International Sport Sciences Congress 8 Görüntülenme
Erişime Açık

The Effect of the Application of Melatonin and Zinc in DMBA-Induced Mammary Carcinoma in Rats on Lipid Peroxidation and Element Metabolism

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

In this study, it was aimed to investigate the effects of application of melatonin and zinc on lipid peroxidation and elemental metabolism in female rats with DMBA-induced mammary carcinoma. The study groups were composed of control, DMBA control and treatment (DMBA+ zinc, DMBA + melatonin and DMBA + zinc+melatonin) groups. Female rats (except the control group) were given a strong carcinogen DMBA. After tumour formation, zinc and melatonin were administered to the treatment groups at a dose of 5 mg/kg/day for 4 weeks. MDA as an indicator of tissue damage and GSH levels as an indicator of anti ...Daha fazlası

Konferans Bildirisi 2018 3rd International Congress of Turkish Neuroendocrinology Society 3 Görüntülenme
Erişime Açık

Increased IL-6 Levels Inhibites by Zinc and Melatonin Support in Rats with Breast Cancer induced by DMBA

BALTACI, Saltuk Buğra | GÜLBAHÇE MUTLU, Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The aim of the present study determines the effect of zinc and melatonin supplementation on IL-6 levels in female rats with breast cancer induced by DMBA (7,12-Dimethylbenz[a]anthracene). Total 42 wistar female rats which was just weaned from milk equally separated 5 groups. Group 1 control, Group 2 DMBA control, Group 3 DMBA+Zinc, Group 4 DMBA+Melatonin, Group 5 DMBA+Zinc+Melatonin. To induce breast cancer, the animals, except those in group 1, were administered 80 mg/kg of DMBA in colza oil (canola) through gavage. The groups which were supplemented with zinc and melatonin were introperitone ...Daha fazlası

Konferans Bildirisi 2018 Internatıonal Academic Research Congress (INES-2018) 8 Görüntülenme
Erişime Açık

Prevention of Increased Brain Cortex Damage by Zinc and Melatonin in Rats with Breast Cancer induced by DMBA

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

ABSTRACT: The aim of the present was study determine the effects of zinc and melatonin on brain tissue (cortex) lipid peroxidation in rats with breast cancer induced by DMBA (7,12-Dimethylbenz[a]anthracene). Total 42 female wistar rats which was just weaned from milk equally separated 5 groups. Group 1 control, Group 2 DMBA control, Group 3 DMBA+ Zinc, Group 4 DMBA + Melatonin, Group 5 DMBA + Zinc +Melatonin. To induce breast cancer 80 mg/kg DMBA was given by gavage in colza oil (except group 1). Zinc and melatonin were supplemented as 5 mg/kg/day for 4 weeks. Brain tissue samples (cortex) wer ...Daha fazlası

Konferans Bildirisi 2018 Internatıonal Academic Research Congress (INES-2018) 5 Görüntülenme
Erişime Açık

The Effect of Support of Zinc and Melatonin on Lipid peroxidation of Various Tissues in Rats with Breast cancer induced by DMBA

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The aim of the present was study determine the effect of zinc and melatonin supplementation on lipid peroxidation of various tissues in female rats with breast cancer induced by DMBA (7,12- Dimethylbenz[a]anthracene). Total 42 Wistar albino female rats were equally separated 5 groups. Group 1 control, Group 2 DMBA control, Group 3 DMBA+Zinc, Group 4 DMBA + Melatonin, Group 5 DMBA+Zinc+Melatonin. Lung, liver, spleen, pancreas and kidney tissue of rats were examined for MDA and GSH by spectrophotometric. The highest lung, liver, spleen, pancreas and kidney MDA levels were determined in group 2 ( ...Daha fazlası

Konferans Bildirisi 2018 Internatıonal Academic Research Congress (INES-2018) 7 Görüntülenme
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