- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır. - İptal tuşuna basarak normal aramaya dönebilirsiniz.
Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası
TÜRKOĞLU, Fatma Nur | ALPA, Şerife | GÜLBAHÇE MUTLU, Elif | ERBAYRAM, Fatma Zehra | ŞEFLEK, Hatice Nur
Background of the Study: Breast cancer, the second most common cause of cancer death, is a global public health problem due to its poor response to treatment and complex aetiology. The MCF-7 cell line is widely used in laboratories around the world for in vitro studies to address this problem. Diazepam is one of the most successful anaesthetics since the beginning of the psychopharmacological revolution. It belongs to a class of benzodiazepines that is often preferred in anaesthesia. Flumazenil is an imidazobenzodiazepine and was the first benzodiazepine antagonist to enter clinical use. The e ...Daha fazlası
ERBAYRAM, Fatma Zehra | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | TÜRKOĞLU, Fatma Nur | ŞEFLEK, Hatice Nur
Background of the Study: Breast cancer, a major cause of cancer-related deaths, is an important health problem due to its inadequate response to treatment and complex etiology. Oxytocin (OT) is a peptide mammalian hormone consisting of nine amino acids. Today, cellular studies of oxytocin have gained importance. Oxytocin has been observed to inhibit cell proliferation in cancer. The biggest advantage of oxytocin therapies is that they provide the organism with cell production on its own and have no side effects. Studies have shown that OT is a factor that stimulates cell proliferation in lung, ...Daha fazlası
Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.