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Bulunan: 325 Adet 0.001 sn
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Erişime Açık

Calixarene modified montmorillonite: A novel design for biosensing applications

SÖNMEZ, Burak | SAYIN, Serkan | YALÇINKAYA, Esra Evrim | AĞ SELECİ, Didem | YILDIZ, Hüseyin Bekir | ODACI DEMİRKOL, Dilek | TİMUR, Suna

Here we report the synthesis, characterization and application of calixarene (Calix) modified montmorillonite (Mt) as a platform for bio-applications such as biomolecule immobilization and biosensing technologies. This modification enhanced the biomolecule immobilization capability of Mt. Initially, amino-functionalised calixarenes (Calix-NH2) were synthesized and used as a modifier. X-ray diffraction, Fourier transform infrared spectroscopy, zeta potential and thermal gravimetric analysis were performed to verify the modification of the clay minerals. For the biosensor construction, Calix-NH2 ...Daha fazlası

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Upgrade of the ALICE Experiment Letter Of Intent

KARASU UYSAL, Ayben | ALICE Collaboration

ALICE (A Large Ion Collider Experiment) is studying the physics of strongly interacting matter, and in particular the properties of the Quark–Gluon Plasma (QGP), using proton–proton, proton–nucleus and nucleus–nucleus collisions at the CERN LHC (Large Hadron Collider). The ALICE Collaboration is preparing a major upgrade of the experimental apparatus, planned for installation in the second long LHC shutdown in the years 2018–2019. These plans are presented in the ALICE Upgrade Letter of Intent, submitted to the LHCC (LHC experiments Committee) in September 2012. In order to fully exploit the p ...Daha fazlası

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On the Interpretation of Melt Quality Assessment of A356 Aluminum Alloy by the Reduced Pressure Test: The Bifilm Index and Its Physical Meaning

ULUDAĞ, Muhammet | ÇETİN,Remzi | DIŞPINAR, Derya | TİRYAKİOĞLU, Murat

The oxide layer on liquid aluminum serves as a protective property to prevent the alloy from further oxidation. However, it has the potential to be a source of porosity when entrained into the bulk of the liquid. For this reason, oxides entrained into aluminum castings have been shown to degrade casting quality. In the current study, the effectiveness of the reduced pressure test in assessing the quality of A356 alloy melts has been investigated under various conditions obtained by changing six different melt parameters. Several metrics, including average pore size, number density of pores, bi ...Daha fazlası

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Multiplicity and transverse momentum evolution of charge-dependent correlations in pp, p–Pb, and Pb–Pb collisions at the LHC

KARASU UYSAL, Ayben | ALICE Collaboration

We report on two-particle charge-dependent correlations in pp, p-Pb, and Pb-Pb collisions as a function of the pseudorapidity and azimuthal angle difference, Δη and Δφ respectively. These correlations are studied using the balance function that probes the charge creation time and the development of collectivity in the produced system. The dependence of the balance function on the event multiplicity as well as on the trigger and associated particle transverse momentum (pT) in pp, p-Pb, and Pb-Pb collisions at sNN−−−√=7, 5.02, and 2.76 TeV, respectively, are presented. In the low transverse mome ...Daha fazlası

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MIPs and Aptamers for Recognition of Proteins in Biomimetic Sensing

MENGER, Marcus | YARMAN, Aysu | ERDŐSSY, Júlia | YILDIZ, Hüseyin Bekir | GYURCSÁNYI, Róbert Ervin | SCHELLER, Frieder Wolfram

Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides for the preparation of aptamers or total chemical synthesis for molecularly imprinted polymers (MIPs). The reproducible production of aptamers is a clear advantage, whilst the preparation of MIPs typically leads to a population of polymers with different binding sites. The realization of binding sites in the total bulk of the MIPs results in a higher binding capacity, however ...Daha fazlası

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Construction of ferrocene modified conducting polymer based amperometric urea biosensor

DERVISEVIC, Muammer | DERVISEVIC, Esma | ŞENEL, Mehmet | ÇEVİK, Emre | YILDIZ, Hüseyin Bekir | ÇAMURLU, Pınar

Herein, an electrochemical urea sensing bio-electrode is reported that has been constructed by fi rstly electropolymerizing 4-(2,5-Di(thiophen-2-yl)-1H-pyrrol-1-yl)aniline monomer (SNS-Aniline) on Pencil Graphite Electrode (PGE), then modifying the polymer coated electrode surface with di-amino-Ferrocene (DAFc) as the mediator, and lastly Urease enzyme through glutaraldehyde crosslinking. The e ff ect of pH, temperature, polymer thickness, and applied potential on the electrode current response was investigated besides performing storage and operational stability experiments with the interferenc ...Daha fazlası

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Synthesis of Various Calix [4] arene Derivatives with Mercaptoalkyl Chains and Their Application in Removing Cr (VI) from Aqueous Solution

SAYIN, Serkan | YILDIZ, Hüseyin Bekir | EYMÜR, Serkan

Four different mercaptoalkyl-substituted calixarene derivatives (5,11,17, 23-tetra-tert-butyl-25,27-bis(3-mercaptopropoxyl)-26,28-dihydroxycalix [4]arene, 25,27-bis(3-mercaptopropoxyl)-26,28-dihydroxycalix[4]arene, 25,27-bis(5-mercaptopentanoxyl)-26,28-dihydroxycalix[4]areneand5,17di-tert-butyl-11,23-di-carboxyl-26,28-bis(3-mercaptopropoxyl)-25,27-dihydroxycalix[4]arene) were synthesized. Their structures were characterized by Fourier transform infrared spectroscopy (FTIR), 1H and 13C NMR spectroscopy, and elemental analysis techniques. Moreover, their extraction capabilities at different para ...Daha fazlası

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Folic-Acid-Modified Conducting Polymer: Electrochemical Detection of the Cell Attachment.

AZAK, Hacer | BARLAS, Fırat Barış | YILDIZ, Hüseyin Bekir | GÜLEÇ, Kadri | DEMİR, Bilal | ODACI DEMİRKOL, Dilek | TİMUR, Suna

Here, postfunctionalization and bioapplication of a π-conjugated polymer named 4-[4H-dithieno(3,2-b:2',3'-d)pyrrol-4-yl]aniline (DTP-aryl-NH2 ) are reported, which is successfully synthesized via electropolymerization onto the glassy carbon electrode. Folic acid (FA) is used to modify the amino functional polymer via N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide chemistry for the further steps. The selective adhesion of folate receptor positive cells on the surface is followed by the electrochemical methods. Cyclic voltammetry and electrochemical impedance s ...Daha fazlası

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A Novel Immobilization Matrix For The Biosensing Of Phenol: Self Assembled Monolayers Of Calixarenes

TAŞÇI, Filiz | SAYIN, Serkan | AĞ SELECİ, Didem | DEMİR, Bilal | AZAK, Hacer | YILDIZ, Hüseyin Bekir | ODACI DEMİRKOL, Dilek | TİMUR, Suna

Aim: The development of calixarene based phenol biosensor. Methods: This study describes the application of a calixarene derivative, 5,17-diamino-25,27-bis(3-thiol-1-oxypropane)-26,28-dihydroxycalix[4]arene (HS-Calix-NH2) which has both amino and thiol functionalities, in the practical surface modifications for biomolecule binding. The structure of HS-Calix-NH2 allows easy inter-action with Au surface and one-step biomolecule immo-bilization. Self-assembled monolayers (SAMs) of p-amino-functionalized mercaptoalkylcalixarene (HS-Calix-NH2) were formed onto the Au electrode. Then, Laccase (Lac) ...Daha fazlası

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Elliptic flow of muons from heavy-flavour hadron decays at forward rapidity in Pb–Pb collisions at √sNN = 2.76 TeV

KARASU UYSAL, Ayben | ALICE Collaboration

The elliptic flow, v2, of muons from heavy-flavour hadron decays at forward rapidity (2.5 < y < 4) is measured in Pb–Pb collisions at √sNN = 2.76 TeV with the ALICE detector at the LHC. The scalar product, two- and four-particle Q cumulants and Lee–Yang zeros methods are used. The dependence of the v2 of muons from heavy-flavour hadron decays on the collision centrality, in the range 0–40%, and on transverse momentum, pT, is studied in the interval 3 < pT < 10 GeV/c. A positive v2 is observed with the scalar product and two-particle Q cumulants in semi-central collisions (10–20% and 20–40% cen ...Daha fazlası

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Centrality dependence of pion freeze-out radii in Pb-Pb collisions at √sNN = 2.76 TeV

KARASU UYSAL, Ayben | ALICE Collaboration

We report on the measurement of freeze-out radii for pairs of identical-charge pions measured in Pb-Pb collisions at √sNN = 2.76 TeV as a function of collision centrality and the average transverse momentum of the pair kT. Three-dimensional sizes of the system (femtoscopic radii), as well as direction-averaged one- dimensional radii are extracted. The radii decrease with kT, following a power-law behavior. This is qualitatively consistent with expectations from a collectively expanding system, produced in hydrodynamic calculations. The radii also scale linearly with ⟨dNch/dη⟩1/3. This behavior ...Daha fazlası

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Event-by-event mean pT fluctuations in pp and Pb–Pb collisions at the LHC

KARASU UYSAL, Ayben | ALICE Collaboration

Event-by-event fluctuations of the mean trans- verse momentum of charged particles produced in pp colli- sions at √s = 0.9, 2.76 and 7 TeV, and Pb–Pb collisions at √sNN = 2.76 TeV are studied as a function of the charged- particle multiplicity using the ALICE detector at the LHC. Dynamical fluctuations indicative of correlated particle emis- sion are observed in all systems. The results in pp collisions show little dependence on collision energy. The Monte Carlo event generators PYTHIA and PHOJET are in qualitative agreement with the data. Peripheral Pb–Pb data exhibit a sim- ilar multiplicity ...Daha fazlası

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