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Erişime Açık

Roles of the lipid peroxidation by-product 4-hydroxynonenal and reductive power in metabolic syndrome

KAYA, Turgut | BABA, Burcu | BERBEROĞLU, Hatice Tuğçe | ÖZTÜRK, Bahadır | KIRAÇ, Cem | HACIŞEVKİ, Onur Aysun

The metabolic syndrome (MetS) is a cluster of three or more risk factors which include high triglycerides, abdominal obesity, high blood pressure, high cholesterol, low HDL, and increased fasting blood glucose. The increase in the prevalence of MetS has been recognized as a public health concern in worldwide. Oxidative stress that has been defined as an imbalance between oxidants and antioxidants in favour of the oxidants, has been associated to metabolic alterations such as metabolic syndrome. 4-Hydroxynonenal (HNE) which results from oxidation of polyunsaturated fatty acyl chains, is one of ...Daha fazlası

Erişime Açık

Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Metabolic Syndrome

BABA, Burcu | KAYA, Turgut | BERBEROĞLU, Hatice Tuğçe | ÖZTÜRK, Bahadır | KIRAÇ, Cem Onur | HACIŞEVKİ, Aysun

Metabolic syndrome (MetS) is a common metabolic disorder that coexist diseases such as dyslipidemia, hypertension, hyperglycemia, and obesity, that increase the risk for developing type 2 diabetes and cardiovascular disease. RAGE (receptor for advanced glycation end-products) is a receptor of the immunoglobulin superfamily, has been implicated in diabetes and its complications, inflammation, and atherosclerosis. RAGE binds multi-ligands such as AGEs (advanced glycation end products) and S100 proteins and binding of ligands activates signaling pathways that involved in cellular stress responses ...Daha fazlası

Erişime Açık

Possible Association of Serum Inflammatory Cytokines and Ferritin Levels with Metabolic Syndrome

BERBEROĞLU, Hatice Tuğçe | BABA, Burcu | KIRAÇ, Cem Onur | ÖZTÜRK, Bahadır | HACIŞEVKİ, Aysun

The metabolic syndrome (MetS) is a common and complex disorder combining obesity, hyperglycemia, dyslipidemia, hypertension, and insulin resistance. It is a major and increasing public-health and clinical challenge worldwide. To date, the mechanisms linking components underlying the MetS remain unclear. However, it has been suggested that inflammation plays an important role in the pathogenesis of MetS. At the present study, we aimed to evaluate serum ferritin and inflammatory cytokine levels and their correlations between individuals with MetS and without MetS. The study included 75 individua ...Daha fazlası

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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