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The purpose of this study was to investigate the effects of zinc and melatonin administration on lipid peroxidation in various tissues in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups in the study: Group 1 (Control), Group 2 (DMBA Control), Group 3 (DMBA+Zinc), Group 4 (DMBA+Melatonin), Group 5 (DMBA+Melatonin, and Zinc). MDA (malondialdehyde) and GSH (glutathione) levels were determined via the spectrophotometric method in the lung, liver, spleen, pancreas, and kidney tissue samples taken from experimental animals. The highest ...Daha fazlası
BACKGROUND: This study aims to investigate the effects of zinc and melatonin supplementation on lipid peroxidation in the brain cortex in DMBA-induced breast cancer in female rats. METHODS: A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: Control (Group 1), DMBA Control (Group 2), DMBA+Zinc (Group 3), DMBA+Melatonin (Group 4), DMBA+Melatonin & Zinc (Group 5). At the end of the study, all animals were sacrifi ced by decapitation and Malondialdehyde (MDA) and glutathione (GSH) levels in brain cortex tissue samples were determined via spectrophotometric methods. RE ...Daha fazlası
ERBAYRAM, Fatma Zehra | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | TÜRKOĞLU, Fatma Nur | ŞEFLEK, Hatice Nur
Background of the Study: Breast cancer, a major cause of cancer-related deaths, is an important health problem due to its inadequate response to treatment and complex etiology. Oxytocin (OT) is a peptide mammalian hormone consisting of nine amino acids. Today, cellular studies of oxytocin have gained importance. Oxytocin has been observed to inhibit cell proliferation in cancer. The biggest advantage of oxytocin therapies is that they provide the organism with cell production on its own and have no side effects. Studies have shown that OT is a factor that stimulates cell proliferation in lung, ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.