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Koleksiyon : Tıp Fakültesi ✕İlgili Araştırmacılar : Merve Aydın Terzioğl ... ✕
Koleksiyon [2]
İlgili Araştırmacılar [20]
Ambargo Durumu [2]
Tam Metin [1]
Yayın Türü [3]
Yazar/lar [20]
Atıf Dizini [4]
Konu Başlıkları [20]
Yayıncı [20]
Yayın Tarihi [7]
Yayın Dili [3]
dc.description.provenance [19]
Doç. Dr. Merve Aydın TerzioğluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ MİKROBİYOLOJİ ANABİLİM DALI/
Süresiz Ambargo

Identification of medically important yeasts by sequence analysis of the internal transcribed spacer and D1/D2 region of the large ribosomal subunit

AYDIN, Merve | KUŞTİMUR, Semra | KALKANCI, Ayşe | DURAN, Tuğçe

Background: The prevalence of opportunistic yeast infections has increased in recent decades as the resultof an increasing immunocompromised patient population.Aims: To evaluate ribosomal RNA (rRNA) gene sequence to identify medically important yeast species, toinvestigate the performance of both the rRNA gene internal transcribed spacer (ITS) and D1/D2 region in identifying clinically relevant yeasts, and to compare these results with those of a standard phenotypicmethod.Methods: Both regions from 50 yeast strains, comprising 45 clinical isolates and 5 reference strains, wereamplified using P ...Daha fazlası

Makale 2019 Rev Iberoam Micol. 2019;36(3):129–138 Revista Iberoamericana de Micología 14 Görüntülenme Süresiz Ambargo
Erişime Açık

Molecular characterization and subtyping of Blastocystis in urticarial patients in Turkey

AYDIN, Merve | YAZICI, Mustafa | DEMİRKAZIK, Mehtap | KOLTAŞ, İsmail Soner | ÇIKMAN, Aytekin | GÜLHAN, Barış | DURAN, Tuğçe | YILMAZ, Aysun | KARA, Murat

Objective: To investigate Blastocystis’ etiologic role and association with gastrointestinal symptomatology in acute and chronic urticaria patients and to identify Blastocystis subtypes responsible for urticaria. Methods: The study included urticaria patients and healthy individuals that presented to our polyclinic between June 2015 and May 2017. The participants were assigned into Group I (137 patients), subdivided into acute (72) and chronic urticaria patients (65), and Group II (129 control individuals). Blastocystis presence was investigated by native-Lugol examination, trichrome staining, ...Daha fazlası

Makale 2019 Asian Pacific Journal of Tropical Medicine 2 Görüntülenme
Erişime Açık

Absence of the mecC gene in methicillin-resistant Staphylococcusaureus isolated from various clinical samples: The first multi-centeredstudy in Turkey

ÇIKMAN, Aytekin | AYDIN, Merve | GÜLHAN, Barış | KARAKEÇİLİ, Faruk | KURTOĞLU, Muhammet Güzel | YÜKSEKKAYA, Şerife | PARLAK, Mehmet | GÜLTEPE, Sümbül Bilge | ÇOPUR ÇİÇEK, Ayşegül | BAYINDIR BİLMAN, Fulya | ÇİFTÇİ, İhsan Hakkı | KARA, Murat | ATMACA, Selahattin | ÖZEKİNCİ, Tuncer

tBackground: mecA is a predefined gene causing methicillin resistance in Staphylococcus aureus (S. aureus)isolates; however, it has been shown that some methicillin-resistant S. aureus (MRSA) strains do notcarry this gene. Recently, in isolates found to be MRSA-positive but mecA-negative, a new resistance gene called mecC, which is a homolog of mecA, has been reported. This study aimed to investigate the mecCand mecA genes in MRSA strains isolated from different geographic regions in Turkey.Methods: The sample of the study consisted of 494 MRSA strains isolated from seven geographical regionsi ...Daha fazlası

Makale 2019 Journal of Infection and Public Health 6 Görüntülenme
Erişime Açık

Borrelia burgdorferi chemotaxis toward tick protein Salp12 contributes to acquisition

MURFIN, Kristen E. | KELINBARD, Ruby | AYDIN, Merve | SALAZAR, Samuel A. | FIKRIG, Erol

Lyme disease is a common tick-borne infection caused by the spirochete Borrelia burgdorferi sensu stricto (s.s.). B. burgdorferi s.s. may utilize chemotaxis, the directional migration towards or away from a chemical stimulus, for transmission, acquisition, and infection. However, the specific signals recognized by the spirochete for these events have not been defined. In this study, we identify an Ixodes scapularis salivary gland protein, Salp12, that is a chemoattractant for the spirochete. We demonstrate that Salp12 is expressed in the I. scapularis salivary glands and midgut and expression ...Daha fazlası

Makale 2019 Ticks and Tick-borne Disease 5 Görüntülenme
Erişime Açık

In vitro anti-candidal and anti-biofilm activity of new ethane sulfonyl hydrazone compound

ÖZTÜRK, Ali | AYDIN, Merve | ÖZDEMİR ÖZMEN, Ümmühan

Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. However, the emergence of resistance to the most common antifungal drugs, also due to biofilm formation, there is an increasing need to design new and more effective antifungals with less toxic. Sulfonyl hydrazones are well-known for their pharmacological effects, such as antifungal and antibacterial potential and can act as an antinociceptive, antidepressant, antineoplastic activity. The aim of this study was to investigate the anti-candidal and anti-biofilm activity o ...Daha fazlası

Konferans Bildirisi 2019 7 Görüntülenme
Erişime Açık

In vitro antifungal and antibiofilm activities of new butane sulfonyl hydrazone compound against medically important yeast

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan

The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası

Konferans Bildirisi 2019 11th Balkan Congress of Microbiology – Microbiologia Balkanica 2019, 6 Görüntülenme
Erişime Açık

Asymptomatic dermatophyte scalp carriage in school children in Erzincan, Turkey

AYDIN, Merve | GÜLHAN, Barış | GÜMRAL, Ramazan | İLKİT, Macit | ÖZTÜRK, Ali

Background: This study aimed to investigate the prevalence of symptomatic tinea capitis infections of the scalp and its asymptomatic carriage in students attending primary schools in Erzincan, Turkey. Materials and Methods: Eighteen primary schools were visited; 1 located in the central district and 17 located in other districts of the Erzincan province. From 2015 November to 2016 April, scalp scrapings were obtained from a total of 1879 students aged 6 to 13 years (mean age: 9.37±1.69) 924 (49.2%) male and 955 (50.8%) female using sterile hairbrushes, and assessed for tinea capitis and asympt ...Daha fazlası

Konferans Bildirisi 2018 Revista Română de Medicină de Laborator 3 Görüntülenme
Erişime Açık

Asymmetrical Dimethylarginine Levels in Hepatitis B Virus-Positive Patients

KARAKEÇİLİ, Faruk | ÇIKMAN, Aytekin | AYDIN, Merve | GÜLHAN, Barış

BACKGROUND: High asymmetrical dimethylarginine (ADMA) levels have been associated with endothelial dysfunction and contribute to the development of several diseases. However, data on the relationship between hepatitis B virus (HBV) and ADMA are limited. The aim of our study was to explore the relationship between ADMA and HBV by comparing the ADMA levels in patients with chronic active hepatitis B (CHB), inactive HBV carriers (carriers), and healthy volunteers (controls). METHODS: The participants were divided into three groups: 90 patients with CHB, 90 HBV carriers, and 90 controls. Serum ADM ...Daha fazlası

Makale 2018 Annals of Laboratory Medicine 4 Görüntülenme
Erişime Açık

Geographical Features and Seroprevalence of Borrelia burgdorferi in Erzincan, Turkey

ÇIKMAN, Aytekin | AYDIN, Merve | GÜLHAN, Barış | KARAKEÇİLİ, Faruk | DEMİRTAŞ, Levent | KESİK, Ozan Arif

Background: We aimed to determine the geographical features and seroprevalence of Borrelia burgdorferi in Erzincan, Turkey, which has a high tick population due to its geographical position and climatic conditions. Methods: From January to December 2014, 368 people living in Erzincan, northeastern Turkey were enrolled. B. burgdorferi IgG antibodies were investigated in the collected serum samples using the ELISA method in 2015. Positive and borderline results were confirmed using the Western Blot (WB) method. Results: Borrelia burgdorferi IgG positivity was found to be 4.1% by ELISA and 2.17% ...Daha fazlası

Makale 2018 Journal of Arthropod-Borne Diseases 3 Görüntülenme
Erişime Açık

Antifungal and anti-biofilm activity of new propane Sulfonyl Hydrazone Against Candida Isolates

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ummuhan

Candidiasis is the most frequently encountered fungal disease that ranges from mild mucosal infections to serious candidaemia and disseminated candidiasis. There are only limited classes of antifungal agents available for physicians to combat Candida infections. In addition, biofilm cells display phenotypic traits that resulting in enhanced resistance to antifungal drugs. Therefore, the limited option to combat fungal threat has raised the interest in seeking alternative antifungal compounds. The aim of this study was to investigate the antifungal and anti-biofilm activity of the new Sulfonyl ...Daha fazlası

Konferans Bildirisi 2019 5th International Congress on Applied Biological Sciences, Sarajevo-Bosnia&Herzegovina 4 Görüntülenme
Erişime Açık

Could interleukin-33 and its suppressor of tumorigenicity 2 (ST2) receptor have a role in cervical human papillomavirus (HPV) infections?

KULHAN, Nur Gözde | KULHAN, Mehmet | AYDIN, Merve | NAYKİ, Ümit | NAYKİ, Cenk | ULUĞ, Paşa | ATA, Nahit | MERTOĞLU, Cuma | ÇIKMAN, Aytekin | SAYAR, İlyas | TÜRKLER, Can

Why most women can clear human papillomavirus (HPV) infections while others can develop permanent infections. The stimulation of immunotolerance of the immune system of the host by the persistent HPV infection may be the answer to this question. Interleukin-33 (IL-33) may play a role in the pathogenesis of HPV infection, this hypothesis was thought to be due to the rapid release of IL-33 from damaged cells following tissue damage, necrosis, and activation of the inflammasome. Thus, in this study, the role of IL33/suppressor of tumorigenicity 2 (ST2) was emphasized in HPV positive and HPV negat ...Daha fazlası

Makale 2019 1 Görüntülenme
Erişime Açık

Evaluation of epidemiological, clinical, and laboratory characteristics and mortality rate of patients with Crimean-Congo hemorrhagic fever in the northeast region of Turkey

KARAKEÇİLİ, Faruk | ÇIKMAN, Aytekin | AYDIN, Merve | BİNAY, Umut Devrim | KESİK, Ozan Arif | ÖZÇİÇEK, Fatih

ackground & objectives : Crimean-Congo hemorrhagic fever (CCHF), an illness characterized by fever and hemorrhage, is caused by a CCHF virus (CCHFV). It is an important public health problem in Turkey. The objective of this study was to evaluate the demographic, clinical, and laboratory characteristics and mortality rates of CCHF patients in the northeast region of Turkey. Methods : A total of 206 patients, diagnosed with CCHF, from northeast region of Turkey were included and evaluated between 2011 and 2017. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) and immunofluoresc ...Daha fazlası

Makale 2019 Journal of Vector Borne Diseases 5 Görüntülenme
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