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Konu Başlıkları : Biofilm ✕İlgili Araştırmacılar : Merve Aydın Terzioğl ... ✕

Koleksiyon [2]

İlgili Araştırmacılar [3]

Ambargo Durumu [1]

Tam Metin [1]

Yayın Türü [2]

Yazar/lar [12]

Atıf Dizini [3]

Konu Başlıkları [11]

Yayıncı [3]

Yayın Tarihi [3]

Yayın Dili [1]

dc.description.provenance [3]

Doç. Dr. Merve Aydın TerzioğluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ MİKROBİYOLOJİ ANABİLİM DALI/

In vitro antifungal and antibiofilm activities of novel sulfonyl hydrazone derivatives against Candida spp.

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZMEN, Ümmühan Özdemir | ŞUMLU, Esra | AYAN, Esra Bilen | KORUCU, Emine Nedime

Background: The aim of this study was to investigate the antifungal and antibiofilm activity of the new sulfonyl hydrazones compound derived from sulphonamides. Methods: In this study, new sulfonyl hydrazone series were synthesized via a green chemistry method. The structures of the synthesized compounds were characterized by elemental analyses and spectroscopic methods. The antifungal activities of the Anaf compounds against Candida strains under planktonic conditions were tested. The biofilm-forming ability of Candida strains was determined and the inhibitory effects of Anaf compounds on Can ...Daha fazlası

Makale 2023 J Mycol Med 0 Görüntülenme

Effect of New Sulfonyl Hydrazone Compounds Against Candida Biofilms

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZDEMİR ÖZMEN, Ümmühan | ŞUMLU, Esra

Objectives: Candidiasis is the most frequently encountered fungal infection, with ranges from mild superficial infections to disseminated candidiasis. Most manifestations of Candidiasis are associated with biofilm formation. Candida biofilms contributes to therapeutic failure due to resistance to antimicrobial agents and causes an increase in mortality rates. For these reasons, finding new drugs and antimicrobial agents are urgently needed. Sulfonyl hydrazones derived from sulfonamide, are well-known for its pharmacological effects, such as antifungal, antibacterial potential activity. This st ...Daha fazlası

Konferans Bildirisi 2021 The Seventh International Mediterranean Symposium on Medicinal and Aromatic Plants MESMAP – 7 0 Görüntülenme

Expression of Sap Genes 1-10 and Biofilm Formation in Candida Spp. Comparison of Healthcare Associated infectıon isolates from Bloodstream with Isolates from Other Sources

NSANGOU, Ahmed Moustapha | SAMADZADE, Rugiyya | DURAN, Tuğçe | MAÇİN, Salih | AYDIN TERZİOĞLU, Merve | FINDIK, Duygu

Candida species are yeast fungi that are common in nature and can cause both superficial and deep infections. According to recent data, Candida species are considered to be the main causative agents of healthcare-associated infections. In this study, it was aimed to determine Candida species, Sap genes and biofilm formation isolated from blood cultures, which are health care-associated infectious agents, and to evaluate them together with antifungal susceptibility tests. Candida spp. were identified by the Vitek 2 Compact method and then the results were verified by multiplex PCR and DNA seque ...Daha fazlası

Konferans Bildirisi 2022 3 rd International Eurasian Mycology Congress (EMC’22) 6 Görüntülenme

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