In vitro antifungal and antibiofilm activities of novel sulfonyl hydrazone derivatives against Candida spp.

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZMEN, Ümmühan Özdemir | ŞUMLU, Esra | AYAN, Esra Bilen | KORUCU, Emine Nedime

Background: The aim of this study was to investigate the antifungal and antibiofilm activity of the new sulfonyl hydrazones compound derived from sulphonamides. Methods: In this study, new sulfonyl hydrazone series were synthesized via a green chemistry method. The structures of the synthesized compounds were characterized by elemental analyses and spectroscopic methods. The antifungal activities of the Anaf compounds against Candida strains under planktonic conditions were tested. The biofilm-forming ability of Candida strains was determined and the inhibitory effects of Anaf compounds on Can ...Daha fazlası