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Bulunan: 21 Adet 0.001 sn
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Bulunan: 21 Adet 0.001 sn
Yayın Dili : en ✕Yazar/lar : GÜLBAHÇE MUTLU, Elif ... ✕
Koleksiyon [2]
İlgili Araştırmacılar [20]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [4]
Yazar/lar [20]
Atıf Dizini [3]
Konu Başlıkları [20]
Yayıncı [15]
Yayın Tarihi [7]
Yayın Dili [1]
Erişime Açık

Effects of Grape Seed Extract on Pancreas Weight in Diabetic Rats

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ARIKOĞLU, Hilal

Introduction: Pancreas is a vital organ that produces metabolic hormones and enzymes. Any change in the function of this organ can directly affect the physiological mechanism in the body. Type II diabetes mellitus is a complex metabolic disease. And, this is emerged from either a failure in insulin secretion from pancreatic beta-cell cells or a decrease in pancreatic beta-cell mass. Despite the use of synthetic drugs in the treatment of metabolic diseases, many traditional plant therapies in the world are still used in the treatment of these diseases. The possible effects of grape seed extract ...Daha fazlası

Araştırma 2018 1st International Congreess on Plant Biology 3 Görüntülenme
Erişime Açık

Comparative Analysis of Agronomic Traits and ISSR Method among Some Soybeans [Glycine Max (L.) Merr.] Genotypes

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif | DURSUN, Ömer | BAĞCI, Seydi Ahmet

In this study, the genetic diversity was investigated among 12 soybeans genotypes using inter simple sequence repeats (ISSR) and agronomic traits. DNA was isolated from the leaves of the genotypes. For molecular characterization, a total of 26 primers of ISSRs and eight agronomic characteristics were evaluated. ISSR analysis revealed 88 polymorphic bands. The genetic diversity among the genotypes according to ISSR analysis and agronomic traits were estimated based on Nei homology and Euclidian distance, respectively, and dendrograms reflecting genetic similarity were constructed using UPGMA an ...Daha fazlası

Makale 2020 KSU J. Agric Nat 4 Görüntülenme
Erişime Açık

The effects of aflatoxin B1 on growth hormone regulated gene-1 and interaction between DNA and aflatoxin B1 in broiler chickens during hatching

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ÖZNURLU, Yasemin | ÖZPARLAK, Haluk

Many types of aflatoxin cause problems for both public and animal health. Aflatoxin B1 (AFB1) is the most toxic and commonly encountered fungal toxin that appears in poultry feed and in feeds stored under unsuitable conditions. AFB1 decreases feed quality, egg production and fertility of hatching eggs. Also, AFB1 alters the development of embryos by infecting eggs. We investigated using sequence analysis the changes caused by different concentrations of AFB1 on the promoter sequences of the growth hormone regulated gene-1 (GHRG-1) in chick embryo at 13, 17, 19 and 21 days incubation. DNA isola ...Daha fazlası

Makale 2018 Biotechnic & Histochemistry 6 Görüntülenme
Erişime Açık

Genotyping of Staphylococcus Aureus Strains Isolated From Bovine Mastitis in Turkey by Using ERIC-PCR Method.

ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Mastitis is an intramammary infection that leads to important economic losses in dairy industry such as increasing the amount of waste milk by affecting the quality and quantity of the milk, removing cows from herd or sending them for slaughter early. Staphylococcus aureus has an important place in the fight against mastitis. In this study, it is aimed to genotyping of the 98 S. aureus isolates that were isolated from bovine mastitis by the polymerase chain reaction of enterobacterial repetitive intergenic consensus (ERIC-PCR). ERIC primers generated DNA products in sizes ranging between ~8000 ...Daha fazlası

Makale 2016 Pakistan Journal of Zoology 6 Görüntülenme
Erişime Açık

The Effect of Melatonin and Zinc Application in Rats Induced Mammary Carcinoma with DMBA on Lipid Peroxidation

GÜLBAHÇE MUTLU, Elif | MENEVŞE, Esma | BALTACI, Abdülkerim Kasım | MOĞULKOÇ, Rasim

Mammary cancer, which is the second most common cause of cancer deaths, is one of the problems of global public health. It is argued that anti estrogenic agents such as melatonin will lead to a new aspect in treatment of breast cancer. In addition, zinc, which plays a crucial role in the etiology of cancer, is vital for many cellular processes, and an important trace mineral. Trace elements are regarded as multiple anti-cancer agents that regulate various biological mechanisms. METHODS: In this study, it was aimed to investigate the effects of melatonin and zinc application on lipid peroxidati ...Daha fazlası

Konferans Bildirisi 2017 International INES Academic Researches Congress 6 Görüntülenme
Erişime Açık

The Effect of Zinc and Melatonin Administration on Lipid Peroxidation, IL-6 Levels, and Element Metabolism in DMBA-Induced Breast Cancer in Rats

GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | MENEVŞE, Esma | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

The purpose of this study was to investigate the effects of zinc and melatonin administration on interleukin-6, lipid peroxidation parameters, and element metabolism in DMBA-induced breast cancer in female rats. A total of 42 recently weaned Wistar rats were divided into 5 groups as follows: control (group 1),DMBA control (group 2),DMBA + zinc (group 3), DMBA + melatonin (group 4), and DMBA + melatonin and zinc (group 5). Malondialdehyde (MDA) and glutathione (GSH) levels in breast tissue and blood samples were determined via spectrophotometric methods. In addition, iron, magnesium, zinc, and ...Daha fazlası

Makale 2020 3 Görüntülenme
Erişime Açık

Mcf-7 Hücre hattında Üzüm (Vitis Vinifera L.) Çekirdeği Ekstraktının Sitotoksik Etkisinin Belirlenmesi

KOYGUN, Gözde | ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Giriş: Kanser, hücre mitozunu kontrol eden genlerin mutasyona uğraması sonucunda hücrelerin kontrolsüz, aşırı ve hızlı bir şekilde çoğalmasına neden olan sistemik bir hastalıktır. Dünya çapındaki tüm yeni kanser teşhislerinin yaklaşık onda birini oluşturan meme kanseri ise, kadınlarda en sık görülen kanser tümörüdür. Metastaz yapma yeteneğine sahip olan tüm kanser hücreleri zamanla bütün organlara yayılabilmektedir. Kanser tedavisinde kullanılan kemoterapötik ilaçların yan etkileri de oldukça fazladır ve bu ilaçlar kanserli hücrelerin yanı sıra sağlıklı hücreleri de etkilemektedir. Bu nedenle ...Daha fazlası

Konferans Bildirisi 2018 1st International Congreess on Plant Biology 4 Görüntülenme
Erişime Açık

The Effects of Resveratrol Supplementation on Oxidant Stress in Old Female Rats with Induced Diabetes

ATACAK, Adem | GÜLBAHÇE MUTLU, Elif | BALTACI, Saltuk Buğra | ÜNAL, Ömer | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Bu çalışmanın amacı diyabet oluşturulmuş yaşlı dişi sıçan modelinde resveratrol desteğinin retinal doku hasarını nasıl etkilediğini araştırmaktır. Bu çalışma Selçuk Üniversitesi Deneysel Tıp Araştırma ve Uygulama Merkezinden temin edilen Wistar cinsi 24 adet erişkin yaşlı dişi sıçan (16 haftalık) üzerinde aynı merkezde gerçekleştirildi. Çalışma protokolü Selçuk Üniversitesi Deneysel Tıp Araştırma ve Uygulama Merkezi Deney Hayvanları Etik Kurulu tarafından onaylandı. Toplam 24 adet yaşlı dişi sıçan kullanılan araştırmada gruplar şu şekilde oluşturuldu: Grup 1. Kontrol, Grup 2. Kontrol + resvera ...Daha fazlası

Konferans Bildirisi 2019 International Congress of Science, Culture and Education 4 Görüntülenme
Erişime Açık

Antioxidant and antimicrobial activity of Mespilus germanica (L.)

GÜLBAHÇE MUTLU, Elif | TANER SARAÇOĞLU, Hatice | ARSLAN, Nursena | ARSLAN, Emine | ZENGİN, Gökhan

Mespilus germanica L. which has an edible fruit is a medicinal plant whose therapeutic effects have historically been emphasized. In this study, we determined antioxidant capacities of methanolic extracts obtained from M. germanica fruits and seeds by using DPPH assay and Folin-Ciocaltaeu method. It was revealed that the total phenolic contents of methanolic extracts of M. germanica seeds (22.94 mgGAE/g extract) were higher than M. germanica fruits (4.67 mgGAE/g extract). Also, the seed extract (9.33 mgTE/g extract) exhibited stronger free radical scavenging activity in DPPH assay as compared ...Daha fazlası

Konferans Bildirisi 2017 Uluslararası Tıbbi ve Aromatik Bitkiler Kongresi 6 Görüntülenme
Erişime Açık

Effects of Soybean Seed (Glycine max) on Some Biochemical Parameters in Streptozotocin- Induced Daibetic Rats

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ARIKOĞLU, Hilal | ERKOÇ KAYA, Dudu

Introduction: Diabetes mellitus is the most widespread and increasingly global prevalence and incidence, and is a chronic metabolic disorder resulting from insulin deficiency or insulin insufficiency. A consequence of this is chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism. In this study, soybean (Glycine max L.) seed extract in wistar rats created experimentally diabetic was aimed to investigate of the effects to some biochemical parameters (Urea, Creatinine, AST, ALT, Cholesterol, Triglycerides, Glucose, LDL, HDL, VLDL) and hyperglycemia. Material and Met ...Daha fazlası

Konferans Bildirisi 2018 1st International Congreess on Plant Biology 4 Görüntülenme
Erişime Açık

Cerebral Ischemia Reperfusion Injury in Rats: Effect of 3’,4’-Dihydroxyflavonol

MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım | MENEVŞE, Esma | BALTACI, Saltuk Buğra | GÜLBAHÇE MUTLU, Elif

The aim of present study was to determine the effect of 3',4'-dihydroxyflavonol (DiOHF) on experimental brain ischemia-reperfusion in rats. The study was performed on the 34 male Wistar-albino rats, weigth 350-400 gr. Experiment groups were designed as 1-Sham; 2-Ischemia-reperfusion; 3-DiOHF+Ischemiareperfusion; 4-Ischemia+DiOHF+Reperfusion; 5- Ischemia-reperfusion+DiOHF. DiOHF was given to animals as 10 mg/kg by intraperitoneal. Cerebral cortex was analyzed for malondyaldehyde (MDA), NO (nitric oxide), xanthine oxidase (XO), glutathione (GSH) and glutathione peroxidase (GPx). Tissue MDA level ...Daha fazlası

Konferans Bildirisi 2018 Internatıonal Academic Research Congress (INES-2018) 7 Görüntülenme
Erişime Açık

Effect of Chronic Running Exercise in Experimental Diabetes Mellitus Rat Model on Lipid Peroxidation in the Hippocampus

YAŞLI, Mehmet | BALTACI, Saltuk Buğra | AKGÜN ÜNAL, Nilüfer | GÜLBAHÇE MUTLU, Elif | MOĞULKOÇ, Rasim | BALTACI, Abdülkerim Kasım

Introduction and Objectives: The aim of this study is to investigate the effect of the chronic running exercise in diabetic rats on lipid peroxidation in hippocampus tissue. The study was carried out in Experimental Medicine Research and Application Center of Selçuk University on adult male Wistar rats that were obtained from the same center. The study protocol was approved by the Ethics Committee of Experimental Animals of Experimental Medicine Research and Application Center of Selcuk University. Methods: A total of 40 rats were equally divided into 4 groups: Group 1, Control, Group 2, Exerc ...Daha fazlası

Sunum 2019 17th International Sport Sciences Congress 8 Görüntülenme
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