The investigation of the antitumoral effect of Cornus mas L in mice with ehrlich solid tumor

YILMAZ, Seher | ALPA, Şerife | GÖÇMEN, Ayşe Yeşim | ÜLGER, Harun | ARSLAN, Esra | YAY, Arzu Hanım | ERTEKİN, Tolga | NİSARİ, Mehtap | YALÇIN, Betül

AIM: Cornus mas L is commonly used due to its anti-inflammatory, anti-carcinogenic and anti-oxidant properties. In the study, the effects of C. mas L extract on a solid tumor were examined in the Ehrlich solid tumor model developed in Balb/C type mice. METHODS: Ehrlich acid tumor (EAT) cells (1x106 EAT cell) from the stock animal were injected subcutaneously (s.c.) through the nape of the mice. Treatment groups of solid tumor-induced animals received 100 mg/kg and 200 mg/kg of C. mas L extract intraperitoneally (i.p.) for 14 days. RESULTS: Tumor volumes and animal weights were found to be stat ...Daha fazlası