- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır. - İptal tuşuna basarak normal aramaya dönebilirsiniz.
TAŞÇI, Filiz | SAYIN, Serkan | AĞ SELECİ, Didem | DEMİR, Bilal | AZAK, Hacer | YILDIZ, Hüseyin Bekir | ODACI DEMİRKOL, Dilek | TİMUR, Suna
Aim: The development of calixarene based phenol biosensor. Methods: This study describes the application of a calixarene derivative, 5,17-diamino-25,27-bis(3-thiol-1-oxypropane)-26,28-dihydroxycalix[4]arene (HS-Calix-NH2) which has both amino and thiol functionalities, in the practical surface modifications for biomolecule binding. The structure of HS-Calix-NH2 allows easy inter-action with Au surface and one-step biomolecule immo-bilization. Self-assembled monolayers (SAMs) of p-amino-functionalized mercaptoalkylcalixarene (HS-Calix-NH2) were formed onto the Au electrode. Then, Laccase (Lac) ...Daha fazlası
ÇEVİK, Emre | CERİT, Alaaddin | TOMBULOĞLU, Hüseyin | SABİT, Hussein | YILDIZ, Hüseyin Bekir
The fabrication of amperometric biosensors based on whole cell Gluconobacter oxydans DSMZ 2343 (G. oxydans) and glucose oxidase (GOx) was performed for the detection of glucose. Glassy carbon electrodes (GCE) were coated with a 10-(4H-dithiyeno [3,2-b:2’,3’-d]pyroll-4-il)decan-1-amine (DTP-alkyl-NH2) polymer using an electropolymerization method and the formed interface was used to connect the bacteria and the enzyme to the electrode. The transfer of electrons from enzyme to electrode was successfully demonstrated by the biocatalytic activity and unique morphology of the conducting polymer. Ch ...Daha fazlası
AZAK, Hacer | KURBANOĞLU, Sevinç | YILDIZ, Hüseyin Bekir | ÖZKAN, Sibel Ayşıl
The synthesis of derivatives of dithionepyrrole is a hot subject that has been studied extensively. In this study, a novel approach for constructing different glucose biosensors using conducting polymers of 4-(4H-dithyinol[3,2-b:2′,3′-d]pyroll-4-yl)aniline and 4-(4H-dithyinol[3,2-b:2′,3′-d]pyroll-4-yl)-[1,1′-biphenyl]-4-amine is proposed. After the synthesis and characterizations of the dithionepyrrole type monomers, they were used in glucose biosensing applications. The surface of gold electrode was modified with mercaptoethane sulfonic acid and p-aminothiophenol functionalized gold nanoparti ...Daha fazlası
KIVRAK, Arif | YILDIZ, Hüseyin Bekir | GÖKYER, Selahattin | ÇARBAŞ, Buket
A novel alkoxy-bridged dithieno (3, 2-B:2’,3’-D) pyrrole (DTP) derivative was synthesized and its corresponding polymer poly(1,2-bis(2-(4H-dithieno[3,2-b:2’,3’-d]pyrrol-4-yl)ethoxy)ethane) (P(DTP-alkoxy-DTP)) was successfully obtained electrochemically. The e ff ects of alkoxy bridge in the structure on the electrochemical and spectroelectrochemical properties of the polymer were also investigated in detail. The results showed that the polymer fi lm exhibits multielectrochromic behavior and a low band gap of 1.82 eV.
AZAK, Hacer | YILDIZ, Hüseyin Bekir | ÇARBAŞ, Buket
Synthesis and electropolymerization of a new conjugated dithieno(3,2-b:20,30-d) pyrole (DTP) derivative, namely, 2-(2-(2-(4H-dithieno[3,2-b:20,30-d]pyrrol-4-yl)ethoxy)ethoxy)ethanamine, (DTP-alkoxy-NH2) monomer are presented. The electrochemical, spectroelectrochemical effects and biosensor capability towards to glucose oxidase enzyme of P(DTP-alkoxy-NH2) polymer fi lm are investigated in detail during the placement of alkoxy-NH2 functional unit in the polymer. Electrochemical and optical results between neutral and oxidized states of the polymer fi lm show that (P(DTP-alkoxy-NH2)) has reversibl ...Daha fazlası
DERVISEVIC, Muamer | DERVISEVIC, Esma | AZAK, Hacer | ÇEVİK, Emre | ŞENEL, Mehmet | YILDIZ, Hüseyin Bekir
In this paper, a novel amperometric xanthine (X) biosensor is constructed by xanthine oxidase (XOx) immobilization on the pencil graphite electrode (PGE). Xanthine oxidase is immobilized using glutaraldehyde (GA) on the electrochemically polymerized conducting polymer film. The detection of xanthine is based on its consumed amount due to the enzymatic reaction of xanthine oxidase. The effects of polymer thickness, applied potential, pH, and temperature were investigated and optimum parameters were found to be five cycles, +5 V, +0.5 V and 30 °C, respectively. Storage stability, operation stabi ...Daha fazlası
DERVISEVIC, Muammer | DERVISEVIC, Esma | ŞENEL, Mehmet | ÇEVİK, Emre | YILDIZ, Hüseyin Bekir | ÇAMURLU, Pınar
Herein, an electrochemical urea sensing bio-electrode is reported that has been constructed by fi rstly electropolymerizing 4-(2,5-Di(thiophen-2-yl)-1H-pyrrol-1-yl)aniline monomer (SNS-Aniline) on Pencil Graphite Electrode (PGE), then modifying the polymer coated electrode surface with di-amino-Ferrocene (DAFc) as the mediator, and lastly Urease enzyme through glutaraldehyde crosslinking. The e ff ect of pH, temperature, polymer thickness, and applied potential on the electrode current response was investigated besides performing storage and operational stability experiments with the interferenc ...Daha fazlası
SAYIN, Serkan | YILDIZ, Hüseyin Bekir | EYMÜR, Serkan
Four different mercaptoalkyl-substituted calixarene derivatives (5,11,17, 23-tetra-tert-butyl-25,27-bis(3-mercaptopropoxyl)-26,28-dihydroxycalix [4]arene, 25,27-bis(3-mercaptopropoxyl)-26,28-dihydroxycalix[4]arene, 25,27-bis(5-mercaptopentanoxyl)-26,28-dihydroxycalix[4]areneand5,17di-tert-butyl-11,23-di-carboxyl-26,28-bis(3-mercaptopropoxyl)-25,27-dihydroxycalix[4]arene) were synthesized. Their structures were characterized by Fourier transform infrared spectroscopy (FTIR), 1H and 13C NMR spectroscopy, and elemental analysis techniques. Moreover, their extraction capabilities at different para ...Daha fazlası
MENGER, Marcus | YARMAN, Aysu | ERDŐSSY, Júlia | YILDIZ, Hüseyin Bekir | GYURCSÁNYI, Róbert Ervin | SCHELLER, Frieder Wolfram
Biomimetic binders and catalysts have been generated in order to substitute the biological pendants in separation techniques and bioanalysis. The two major approaches use either "evolution in the test tube" of nucleotides for the preparation of aptamers or total chemical synthesis for molecularly imprinted polymers (MIPs). The reproducible production of aptamers is a clear advantage, whilst the preparation of MIPs typically leads to a population of polymers with different binding sites. The realization of binding sites in the total bulk of the MIPs results in a higher binding capacity, however ...Daha fazlası
AZAK, Hacer | BARLAS, Fırat Barış | YILDIZ, Hüseyin Bekir | GÜLEÇ, Kadri | DEMİR, Bilal | ODACI DEMİRKOL, Dilek | TİMUR, Suna
Here, postfunctionalization and bioapplication of a π-conjugated polymer named 4-[4H-dithieno(3,2-b:2',3'-d)pyrrol-4-yl]aniline (DTP-aryl-NH2 ) are reported, which is successfully synthesized via electropolymerization onto the glassy carbon electrode. Folic acid (FA) is used to modify the amino functional polymer via N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide chemistry for the further steps. The selective adhesion of folate receptor positive cells on the surface is followed by the electrochemical methods. Cyclic voltammetry and electrochemical impedance s ...Daha fazlası
In this study, a novel amperometric glucose biosensor based on a selenium comprising conducting polymer and calixarene was developed. Firstly, poly(2-(2-octyldodecyl)-4,7-di(selenoph-2-yl)-2H-benzo[d][1,2,3]triazole), poly((SBTz)) was electrodeposited onto a graphite electrode by an electropolymerization technique. Then, a newly synthesized calixarene and gold nanoparticle (AuNP) mixture was used for the improvement of biosensor characteristics. GOx, as a model enzyme was immobilized on the modified electrode surface. The constructed surface serves as a sufficient immobilization platform for t ...Daha fazlası
SAYIN, Serkan | AZAK, Hacer | YILDIZ, Hüseyin Bekir | ÇAMURLU, Pınar | UYSAL AKKUŞ, Gülderen | TOPPARE, Lale | ERSÖZ, Mustafa
Two novel calix[n]arene-adorned gold electrodes producing high photocurrent intensities were successfully constructed by embedding gold electrode surfaces with both P(4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine) conducting polymer and 4-mercaptoboronic acid-functionalized semiconductor CdS nanoparticles to facilitate the binding of calix[n]arene sulfonic acids with nanoparticles. This structure enabled an electron transfer cascade that both induced effective charge separation and efficiently generated photocurrent. The prepared electrodes were used to generate photocurrent by relying o ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.