- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır. - İptal tuşuna basarak normal aramaya dönebilirsiniz.
AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan
The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası
Background: The aim of this study was to investigate the antifungal and antibiofilm activity of the new sulfonyl hydrazones compound derived from sulphonamides. Methods: In this study, new sulfonyl hydrazone series were synthesized via a green chemistry method. The structures of the synthesized compounds were characterized by elemental analyses and spectroscopic methods. The antifungal activities of the Anaf compounds against Candida strains under planktonic conditions were tested. The biofilm-forming ability of Candida strains was determined and the inhibitory effects of Anaf compounds on Can ...Daha fazlası
Artemisinin is a sesquiterpene lactone derivative of Artemisia annua L. Previous research has shown that artemisinin and its derivatives have important pharmacological properties. Candida species are opportunistic infections with high mortality and morbidity rates worldwide. There is growing evidence that natural agents have the ability to treat Candida infections. The demand for new drugs has increased in recent years due to treatment costs, toxicity and resistance to conventional antifungal drugs. The aim of this study was to investigate the antifungal and antibiofilm activity of artemisinin ...Daha fazlası
ÖZTÜRK, Ali | ABDULMAJED, Olkar | AYDIN TERZİOĞLU, Merve
Aim: This study was aimed to evaluate the antifungal, antibiofilm, and anti-filamentation activities of three commonly used biocides against clinical Candida isolates. Material and Methods: The in vitro activities of benzalkonium chloride (BZC), chlorhexidine digluconate (CHX), and triclosan (TRC) were studied against three Candida (C. albicans, C. parapsilosis, and C. glabrata) isolates. The isolates were identified, using the germ tube test, Cornmeal agar, and ID32 C (bioMerieux, France) kit. Antifungal susceptibility of these isolates was determined using the broth microdilution method. Ant ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.