Investigating thiol/disulfide homeostasis in acute migraine attack with aura

HORASANLI, Bahriye | AYDIN TERZİOĞLU, Merve | ŞUMLU, Esra | ÇALIŞKAN SAK, Kaniye Zeynep | ÖZŞAHİN, Aysun | FIRAT OĞUZ, Esra | EREL, Özcan

Aim: This study investigates thiol-disulfide hemostasis, which plays a role in the pathophysiology of migraine and is a new marker for oxidative stress in migraine with aura and healthy controls. Material and methods: The study included 53 healthy controls and 60 patients who presented to Konya City Hospital Neurology Outpatient Clinic with headache and were diagnosed migraine with aura. First, written informed consent was obtained from patients and controls. Then, dynamic thiol-disulfide homeostasis was investigated following the automated spectrophotometric method in serum samples of migrain ...Daha fazlası