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Bulunan: 20 Adet 0.000 sn
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Filtreler
Bulunan: 20 Adet 0.000 sn
Yazar/lar : TÜRKOĞLU, Fatma Nur ... ✕
Koleksiyon [2]
İlgili Araştırmacılar [20]
Ambargo Durumu [1]
Tam Metin [1]
Yayın Türü [3]
Yazar/lar [20]
Atıf Dizini [4]
Konu Başlıkları [20]
Yayıncı [16]
Dergi Adı [2]
Yayın Tarihi [6]
Dergi Sayısı [1]
Yayın Dili [3]
dc.description.provenance [11]
Erişime Açık

In Vitro Activity of Coenzymeq10 Loaded Mesoporous Silica Nanoparticles Against Mcf-7 Cells

GÜLBAHÇE MUTLU, Elif | ŞEFLEK, Hatice Nur | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur

Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası

Konferans Bildirisi 2023 İKİNCİ ULUSLARARASI SELÇUK SAĞLIK BİLİMLERİ KONGRESİ 1 Görüntülenme
Erişime Açık

Determination of Cytoxic Effects of Diazepam and Flumazenil in MCF-7 Cell Line

TÜRKOĞLU, Fatma Nur | ALPA, Şerife | GÜLBAHÇE MUTLU, Elif | ERBAYRAM, Fatma Zehra | ŞEFLEK, Hatice Nur

Background of the Study: Breast cancer, the second most common cause of cancer death, is a global public health problem due to its poor response to treatment and complex aetiology. The MCF-7 cell line is widely used in laboratories around the world for in vitro studies to address this problem. Diazepam is one of the most successful anaesthetics since the beginning of the psychopharmacological revolution. It belongs to a class of benzodiazepines that is often preferred in anaesthesia. Flumazenil is an imidazobenzodiazepine and was the first benzodiazepine antagonist to enter clinical use. The e ...Daha fazlası

Konferans Bildirisi 2023 Selçuk Üniversitesi 2 Görüntülenme
Erişime Açık

Determination Of Cytoxic Effects Of Oxytocin And Atosiban Mcf-7 Cell Line

ERBAYRAM, Fatma Zehra | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | TÜRKOĞLU, Fatma Nur | ŞEFLEK, Hatice Nur

Background of the Study: Breast cancer, a major cause of cancer-related deaths, is an important health problem due to its inadequate response to treatment and complex etiology. Oxytocin (OT) is a peptide mammalian hormone consisting of nine amino acids. Today, cellular studies of oxytocin have gained importance. Oxytocin has been observed to inhibit cell proliferation in cancer. The biggest advantage of oxytocin therapies is that they provide the organism with cell production on its own and have no side effects. Studies have shown that OT is a factor that stimulates cell proliferation in lung, ...Daha fazlası

Konferans Bildirisi 2023 Selçuk Üniversitesi 0 Görüntülenme
Erişime Açık

Determination of The Cytotoxic Effect of Propylthiouracil Loaded Mesoporous Silica on Mcf-7 Cell Line

GÜLBAHÇE MUTLU, Elif | ŞEFLEK, Hatice Nur | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur

Background of the Study: Nanomedicine is being investigated nanotechnology-based solutions to medical problems to increase the bioavailability of drugs and reduce side effects. The ultimate goal is to enable more effective and patient-friendly treatment regimens by reducing drug concentration and dosing frequency, offering easier administration and improving safety. Silica-based nanoparticles are widely used in nanomedicine and are emerging as a promising next-generation material for biological applications. Mesoporous silica nanoparticles (MSNs) have been used as drug nanocarriers in breast c ...Daha fazlası

Konferans Bildirisi 2023 SELÇUK ÜNİVERSİTESİ 0 Görüntülenme
Erişime Açık

Determination of Antioxidant and Anticancer Activities of C. Sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadime | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası

Makale 2023 Medical Records5 0 Görüntülenme
Erişime Açık

Determination of Antioxidant and Anticancer Activities of C. sativa Leaf Extracts on MCF7 Human Breast Cancer Cell Line

BEYAZYÜZ, Fadiem | GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | KULAÇ, Şemsettin

Aim: In this study, it was aimed to determine the total phenolic content, flavonoid content, and antioxidant activity of Castanea sativa Mill. (chestnut) leaf extract and their anti-proliferative effect on MCF 7 cell line. Materials and Methods: It determined antioxidant capacities by using DPPH assay, total phenolic content by using Folin-Ciocaltaeu method and Total flavonoid content by aluminum chloride colorimetric method in the ethanolic extracts of Chesnut leaf. In addition, the anti-proliferative effect of chestnut leaf extract was determined by XTT method in MCF7 breast cell line. The l ...Daha fazlası

Makale 2023 Medical Records - International Medical Journal 5 Görüntülenme
Erişime Açık

İnsan Kuru Kafataslarında Foramen Jugulare’nin Morfometrik ve Makroskobik Analizi

AKIN SAYGIN, Duygu | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife | TÜRKOĞLU, Fatma Nur | BÜYÜKMUMCU, Mustafa

Jugular foramen is a long irregularly shaped foramen at base of human skull lies between occipital bone and petrous part of temporal bone. This study was conducted on 103 adult dry skulls in collections of Necmettin Erbakan University Meram Medicine Faculty Anatomy Labratory and Karatay Medicine Faculty Anatomy Labratory. Digital caliper was used for jugular foramen measurements. We studied adult human skull of unknown sex and measured sagittal and transverse diameter of Jugular foramen. Jugular foramen were also observed for the presence of dome, septation and right or left dominance. We also ...Daha fazlası

Konferans Bildirisi 2018 1st International Congress On Sports, Anthropology, Nutrition, Anatomy and Radiology 5 Görüntülenme
Erişime Açık

Morpometric Analysis Of Dry Femurs Collected From Central Anatolia

ALPA, Şerife | TÜRKOĞLU, Fatma Nur | TÜRKOĞLU, Burak | AYDIN, Methi Sipan

The femur is the largest bone in the human skeleton. We aimed to take the morphometric measurements of the femur and to evaluate the relations between these measurements. The study was carried out in the Department of Anatomy, Faculty of Medicine, KTO Karatay University. A total of 268 bones, 124 right and 144 left, were included in the study. Photographs of the femurs were taken at equal distances and using millimetric paper for measurements. Measurements were taken with image-j program. In our study, femur length, femoral cord length, femoral diaphyseal curvature, thickness measurements from ...Daha fazlası

Konferans Bildirisi 2022 International Congress of Education and Science- INCES 2022 6 Görüntülenme
Erişime Açık

Investigation Of Morphometry Of Lumbal And Sacral Regions In Sacroiliac Joint Diseases With Magnetic Resonance Imaging-Prereport Submission

ALPA, Şerife | TÜRKOĞLU, Fatma Nur | BAĞÇACI, Sinan | ÖDEV, Kemal

Background: The sacroiliac joint complex is the most important mechanical axis structure in the human body. The force from the lower extremities is mainly transferred to the spine through this joint. The sacroiliac joint is a part that is frequently evaluated in painful conditions of the lumbar region, pelvis and lower extremities. It has been of interest to examine the associations of sacroiliac joint pain with joint morphometry to optimize the management of sacroiliac joint patients. Therefore, in our study, it was aimed to take morphometric measurements in the lumbar and sacral regions of p ...Daha fazlası

Konferans Bildirisi 2022 1ST INTERNATIONAL CONGRESS of SELÇUK HEALTH SCIENCES 5 Görüntülenme
Erişime Açık

Determination Of Cytotoxic Effect Of Castanea Sativa Mill Loaded Nanoporous Glass On The MCF-7 Cell Line

GÜLBAHÇE MUTLU, Elif | ALPA, Şerife | ERTUŞ, Emre Burak | ERBAYRAM, Fatma Zehra | TÜRKOĞLU, Fatma Nur | BEYAZYÜZ, Fadime | KULAÇ, Şemsettin

Background: Nanoporous glasses (NGC) are amorphous materials with high surface area and high pore volume produced by selective leaching of phase separated alkaliborisilicate glasses in acidic solution. It also has a high SiO2 content and stands out as a promising new generation material in biological applications. Cestanea sativa (Mill) used in this study has valuable nutrients and is considered an important plant in many countries including Turkey. Matherials and Methods: In our study, the loading capacity of C. sativa (Mill) ethanolic extract loaded into NGC and the cytotoxic effect of C. sa ...Daha fazlası

Konferans Bildirisi 2022 1ST INTERNATIONAL CONGRESS of SELÇUK HEALTH SCIENCES 5 Görüntülenme
Erişime Açık

Multipl Skleroz hastalarında bazal çekirdeklerin hacimlerinin değerlendirilmesi; ön rapor sunumu

TÜRKOĞLU, Fatma Nur | ÜNVER DOĞAN, Nadire | ÖZTÜRK, Şerefnur | FAZLIOĞULLARI, Zeliha | KOPLAY, Mustafa | KARABULUT, Ahmet Kağan

Objective: The aim of our study is to analyze Magnetic Resonance Imaging (MRI) data of Multiple Sclerosis (MS) patients with VolBrain, to make volumetric calculations for total intracranial volume and basal nuclei, and to determine the statistical differences of the obtained data in terms of gender, lateralization and MS subtypes. Methods: In our study, MRI data of 156 MS patients were calculated using VolBrain, right-left and total intracranial volumes and basal nuclei volumes, and volumetric differences between MS subtypes and gender were statistically examined. Correlation analysis between ...Daha fazlası

Konferans Bildirisi 2023 ACTA MEDICA formerly Hacettepe Medical Journal 0 Görüntülenme
Erişime Açık

Morphometric Evaluation of Rarely Seen Supratrochlear Foramen and Supracondylar Process in the Humerus in Turkish Population

AKIN SAYGIN, Duygu | TÜRKOĞLU, Fatma Nur | TOKPINAR, Adem | UÇAR, Sümeyye | YILMAZ, Seher | AYDIN KABAKÇI, Anıl Didem | ALPA, Şerife

Abstract Background: Sometimes seen distal to humerus foramen supratrochleare and supracondylar process are rare variations. Supracondylar process is a variations observed on the distal side of humerus. The supracondylar process is a variant located 1/3 distal side of the humerus. The supratrochlear foramen may appear between the coronoid fossa and olecranon fossa. Since the foramen may appear in a semi-transparent form, it may be misdiagnosed as an osteolytic lesion. The aim of the present study was to identify the prevalence and morphology of supratrochlear foramen and the supracondylar proc ...Daha fazlası

Makale 2022 Harran Üniversitesi Tıp Fakültesi Dergisi 3 Görüntülenme
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