- Eklemek veya çıkarmak istediğiniz kriterleriniz için 'Dahil' / 'Hariç' seçeneğini kullanabilirsiniz. Sorgu satırları birbirine 'VE' bağlacı ile bağlıdır. - İptal tuşuna basarak normal aramaya dönebilirsiniz.
Background: The aim of this study was to investigate the antifungal and antibiofilm activity of the new sulfonyl hydrazones compound derived from sulphonamides. Methods: In this study, new sulfonyl hydrazone series were synthesized via a green chemistry method. The structures of the synthesized compounds were characterized by elemental analyses and spectroscopic methods. The antifungal activities of the Anaf compounds against Candida strains under planktonic conditions were tested. The biofilm-forming ability of Candida strains was determined and the inhibitory effects of Anaf compounds on Can ...Daha fazlası
Aim: This study investigates thiol-disulfide hemostasis, which plays a role in the pathophysiology of migraine and is a new marker for oxidative stress in migraine with aura and healthy controls. Material and methods: The study included 53 healthy controls and 60 patients who presented to Konya City Hospital Neurology Outpatient Clinic with headache and were diagnosed migraine with aura. First, written informed consent was obtained from patients and controls. Then, dynamic thiol-disulfide homeostasis was investigated following the automated spectrophotometric method in serum samples of migrain ...Daha fazlası
Objectives: Candidiasis is the most frequently encountered fungal infection, with ranges from mild superficial infections to disseminated candidiasis. Most manifestations of Candidiasis are associated with biofilm formation. Candida biofilms contributes to therapeutic failure due to resistance to antimicrobial agents and causes an increase in mortality rates. For these reasons, finding new drugs and antimicrobial agents are urgently needed. Sulfonyl hydrazones derived from sulfonamide, are well-known for its pharmacological effects, such as antifungal, antibacterial potential activity. This st ...Daha fazlası
Artemisinin is a sesquiterpene lactone derivative of Artemisia annua L. Previous research has shown that artemisinin and its derivatives have important pharmacological properties. Candida species are opportunistic infections with high mortality and morbidity rates worldwide. There is growing evidence that natural agents have the ability to treat Candida infections. The demand for new drugs has increased in recent years due to treatment costs, toxicity and resistance to conventional antifungal drugs. The aim of this study was to investigate the antifungal and antibiofilm activity of artemisinin ...Daha fazlası
Kronik böbrek hastalığı (KBH) yüksek morbidite ve mortaliteye sahip yaygın görülen ilerleyici bir hastalıktır. KBH tedavisinin çoğunlukla semptomatik olduğu göz önüne alındığında, böbrek fonksiyonlarını korumaya yönelik profilaktik tedaviler önem kazanmaktadır. Son yıllarda yapılan çalışmalar, bağırsak mikrobiyotası böbrek eksenindeki değişikliklerin ve disbiyozun özellikle üremik toksinlerin düzeyini ve kardiyovasküler riski arttırarak KBH’nin gelişimini ve ilerlemesini etkileyebileceğini göstermektedir. Ayrıca, araştırmalar probiyotik, prebiyotik, sinbiyotik ve fekal mikrobiyota transplantas ...Daha fazlası
Bu bölümün sonunda bruselloz hastalığının klinik belirti ve bulguları, Brucella spp.’nin temel mikrobiyolojik özellikleri, hayvanlarda ve insanlarda bulaş yolları ve hastalık yapan türleri, bruselloz tanısında kullanılacak laboratuvar yöntemleri ve tedavisi hakkında detaylı bilgiye sahip olabileceksiniz.
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.