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Erişime Açık

Effects of Grape Seed Extract on Pancreas Weight in Diabetic Rats

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ARIKOĞLU, Hilal

Introduction: Pancreas is a vital organ that produces metabolic hormones and enzymes. Any change in the function of this organ can directly affect the physiological mechanism in the body. Type II diabetes mellitus is a complex metabolic disease. And, this is emerged from either a failure in insulin secretion from pancreatic beta-cell cells or a decrease in pancreatic beta-cell mass. Despite the use of synthetic drugs in the treatment of metabolic diseases, many traditional plant therapies in the world are still used in the treatment of these diseases. The possible effects of grape seed extract ...Daha fazlası

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The effects of aflatoxin B1 on growth hormone regulated gene-1 and interaction between DNA and aflatoxin B1 in broiler chickens during hatching

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ÖZNURLU, Yasemin | ÖZPARLAK, Haluk

Many types of aflatoxin cause problems for both public and animal health. Aflatoxin B1 (AFB1) is the most toxic and commonly encountered fungal toxin that appears in poultry feed and in feeds stored under unsuitable conditions. AFB1 decreases feed quality, egg production and fertility of hatching eggs. Also, AFB1 alters the development of embryos by infecting eggs. We investigated using sequence analysis the changes caused by different concentrations of AFB1 on the promoter sequences of the growth hormone regulated gene-1 (GHRG-1) in chick embryo at 13, 17, 19 and 21 days incubation. DNA isola ...Daha fazlası

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Mcf-7 Hücre hattında Üzüm (Vitis Vinifera L.) Çekirdeği Ekstraktının Sitotoksik Etkisinin Belirlenmesi

KOYGUN, Gözde | ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Giriş: Kanser, hücre mitozunu kontrol eden genlerin mutasyona uğraması sonucunda hücrelerin kontrolsüz, aşırı ve hızlı bir şekilde çoğalmasına neden olan sistemik bir hastalıktır. Dünya çapındaki tüm yeni kanser teşhislerinin yaklaşık onda birini oluşturan meme kanseri ise, kadınlarda en sık görülen kanser tümörüdür. Metastaz yapma yeteneğine sahip olan tüm kanser hücreleri zamanla bütün organlara yayılabilmektedir. Kanser tedavisinde kullanılan kemoterapötik ilaçların yan etkileri de oldukça fazladır ve bu ilaçlar kanserli hücrelerin yanı sıra sağlıklı hücreleri de etkilemektedir. Bu nedenle ...Daha fazlası

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Effects of Soybean Seed (Glycine max) on Some Biochemical Parameters in Streptozotocin- Induced Daibetic Rats

GÜLBAHÇE MUTLU, Elif | ARSLAN, Emine | ARIKOĞLU, Hilal | ERKOÇ KAYA, Dudu

Introduction: Diabetes mellitus is the most widespread and increasingly global prevalence and incidence, and is a chronic metabolic disorder resulting from insulin deficiency or insulin insufficiency. A consequence of this is chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism. In this study, soybean (Glycine max L.) seed extract in wistar rats created experimentally diabetic was aimed to investigate of the effects to some biochemical parameters (Urea, Creatinine, AST, ALT, Cholesterol, Triglycerides, Glucose, LDL, HDL, VLDL) and hyperglycemia. Material and Met ...Daha fazlası

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The Cytotoxic Effects of Soybean (Glycine max L.) in Breast Cancer MCF-7 Cell Line In Vitro

KOYGUN, Gözde | ARSLAN, Emine | GÜLBAHÇE MUTLU, Elif

Aim of the study: Breast cancer is one of the most noticeable disease in women aged 20-59 years also it is expected to account for 30% of all new cancer diagnoses in women in 2016, Long-term use ofsoybean (Glycine max 1.) may prevent the progression of cancer. However, the molecular mechanism forthe functions of soybean remains unclear. So we decided to see how effective soybeans are on MCF-7Cell lines. Materials and Methods: Human breast cancer cell lines MCF-7 were treated with different concen-trations of methanol extract of soybean seeds. The growth rate was evaluated by XTT tests for 48 a ...Daha fazlası

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve cerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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