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Bulunan: 2 Adet 0.001 sn

Yayın Dili : eng ✕İlgili Araştırmacılar : Esra Şumlu ✕

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Dr. Öğr. Üyesi Esra ŞumluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/DAHİLİ TIP BİLİMLERİ BÖLÜMÜ/TIBBİ FARMAKOLOJİ ANABİLİM DALI/

Effect of New Sulfonyl Hydrazone Compounds Against Candida Biofilms

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZDEMİR ÖZMEN, Ümmühan | ŞUMLU, Esra

Objectives: Candidiasis is the most frequently encountered fungal infection, with ranges from mild superficial infections to disseminated candidiasis. Most manifestations of Candidiasis are associated with biofilm formation. Candida biofilms contributes to therapeutic failure due to resistance to antimicrobial agents and causes an increase in mortality rates. For these reasons, finding new drugs and antimicrobial agents are urgently needed. Sulfonyl hydrazones derived from sulfonamide, are well-known for its pharmacological effects, such as antifungal, antibacterial potential activity. This st ...Daha fazlası

Konferans Bildirisi 2021 The Seventh International Mediterranean Symposium on Medicinal and Aromatic Plants MESMAP – 7 0 Görüntülenme

In vitro effects of newly synthesized propane sulfonyl hydrazone derivatives on rat myometrial contractions

ŞUMLU, Esra | ÖZDEMİR ÖZMEN, Ummuhan | ÇALIŞKAN SAK, Kaniye Zeynep | YAVUZ, Ayça | BİLEN AYAN, Esra | KUTLU, Selim

This study aimed to investigate the potential of newly synthesized sulfonyl hydrazone (SH) derivatives to modulate contractions in isolated rat myometrium. For this purpose, the structures of SH compounds were characterized by elemental analyses and spectroscopic methods. Virgin female rats were obtained from KONUDAM Experimental Animal Research Centre (Konya, Turkey). Longitudinal myometrial strips, rapidly isolated post-decapitation, were rapidly inserted into a tissue bath containing Krebs' solution to monitor spontaneous contractions. Separate strips from each rat were treated with two dif ...Daha fazlası

Konferans Bildirisi 2023 6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023) 7 Görüntülenme

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