BACKGROUND: The present study was designed to compare the effectiveness of topical silver sulfadiazine (SSD) and Ankaferd Blood Stopper® (ABS) usage in experimental partial-thickness burns in rats. METHODS: Twenty-one male Wistar albino rats weighing 250-290 (range: 270±19) g were used in the present study. A round brass probe that was specifically designed (3×3 cm diameter) was used to induce the burns in rats. After the presence of partial-thickness burns was confirmed, the rats were divided into three groups: Group 1 (ABS group) Ankaferd Blood Stopper® pad, Group 2 (SSD group) silver sulfadiazine (Silverdin®), and Group 3 (Control group) 1% isotonic saline solution-impregnated pad. The healing period was followed up clinically and histopathologically. The day on which 50% and 80% of re-epithelization at first were detected for each rat was also recorded. RESULTS: The mean times of 50% and 80% of re-epithelization at first were 10.8 days, 13.8 days, and 16.8 days in Groups 1, 2, and 3, respectively (p<0.001), and 16.4 days, 19.7 days, and 25.2 days, respectively (p<0.001). The mean inflammatory scores were also found to be better in the ABS group than in other groups (p<0.05). CONCLUSION: Our study showed that ABS has better results for the healing of the burn wound than SSD in experimental partialthickness burns in rats. © 2019 Turkish Association of Trauma and Emergency Surgery.
Eser Adı (dc.title) | Comparison of Ankaferd Blood Stopper and silver sulfadiazine use in burn wounds: An experimental study |
Yayın Türü (dc.type) | Makale |
Yazar/lar (dc.contributor.author) | AY, Serden |
Yazar/lar (dc.contributor.author) | ÜNLÜ, Yaşar |
DOI Numarası (dc.identifier.doi) | 10.14744/tjtes.2019.38265 |
Atıf Dizini (dc.source.database) | Scopus |
Konu Başlıkları (dc.subject) | Ankaferd Blood Stopper |
Konu Başlıkları (dc.subject) | Silver Sulfadiazine |
Konu Başlıkları (dc.subject) | Experimental Study |
Konu Başlıkları (dc.subject) | Burn |
Yayıncı (dc.publisher) | Turkish Association of Trauma and Emergency Surgery |
Yayın Tarihi (dc.date.issued) | 2019 |
Kayıt Giriş Tarihi (dc.date.accessioned) | 2020-08-07T12:50:34Z |
Açık Erişim tarihi (dc.date.available) | 2020-08-07T12:50:34Z |
Kaynak (dc.source) | Ulusal Travma ve Acil Cerrahi Dergisi |
ISSN (dc.identifier.issn) | 1306696X (ISSN) |
Özet (dc.description.abstract) | BACKGROUND: The present study was designed to compare the effectiveness of topical silver sulfadiazine (SSD) and Ankaferd Blood Stopper® (ABS) usage in experimental partial-thickness burns in rats. METHODS: Twenty-one male Wistar albino rats weighing 250-290 (range: 270±19) g were used in the present study. A round brass probe that was specifically designed (3×3 cm diameter) was used to induce the burns in rats. After the presence of partial-thickness burns was confirmed, the rats were divided into three groups: Group 1 (ABS group) Ankaferd Blood Stopper® pad, Group 2 (SSD group) silver sulfadiazine (Silverdin®), and Group 3 (Control group) 1% isotonic saline solution-impregnated pad. The healing period was followed up clinically and histopathologically. The day on which 50% and 80% of re-epithelization at first were detected for each rat was also recorded. RESULTS: The mean times of 50% and 80% of re-epithelization at first were 10.8 days, 13.8 days, and 16.8 days in Groups 1, 2, and 3, respectively (p<0.001), and 16.4 days, 19.7 days, and 25.2 days, respectively (p<0.001). The mean inflammatory scores were also found to be better in the ABS group than in other groups (p<0.05). CONCLUSION: Our study showed that ABS has better results for the healing of the burn wound than SSD in experimental partialthickness burns in rats. © 2019 Turkish Association of Trauma and Emergency Surgery. |
Yayın Dili (dc.language.iso) | en |
Tek Biçim Adres (dc.identifier.uri) | http://hdl.handle.net/20.500.12498/2773 |