Doç. Dr. Merve Aydın TerzioğluKTO KARATAY ÜNİVERSİTESİ/TIP FAKÜLTESİ/TEMEL TIP BİLİMLERİ BÖLÜMÜ/TIBBİ MİKROBİYOLOJİ ANABİLİM DALI/

In vitro anti-candidal and anti-biofilm activity of new ethane sulfonyl hydrazone compound

ÖZTÜRK, Ali | AYDIN, Merve | ÖZDEMİR ÖZMEN, Ümmühan

Candida species cause cutaneous and systemic infections with a high mortality rate, especially in immunocompromised patients. However, the emergence of resistance to the most common antifungal drugs, also due to biofilm formation, there is an increasing need to design new and more effective antifungals with less toxic. Sulfonyl hydrazones are well-known for their pharmacological effects, such as antifungal and antibacterial potential and can act as an antinociceptive, antidepressant, antineoplastic activity. The aim of this study was to investigate the anti-candidal and anti-biofilm activity o ...Daha fazlası

Konferans Bildirisi 2019 7 Görüntülenme

In vitro antifungal and antibiofilm activities of new butane sulfonyl hydrazone compound against medically important yeast

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ümmühan

The prevalence of fungal infections has increased in the last two decades in parallel with the increasing number of immunosuppressed patients. The excessive use of antifungal agents is causing the accumulation of multi-resistance phenotypes in many fungal strains. Consequently, new alternative agents to conventional antifungal agents are urgently needed to prevent the emergence of fungal resistance. Sulfonyl hydrazone derived from sulfonamide, are well-known for their pharmacological effects, such as antifungal, antibacterial potential, and antineoplastic activity. This study aimed to investig ...Daha fazlası

Konferans Bildirisi 2019 11th Balkan Congress of Microbiology – Microbiologia Balkanica 2019, 6 Görüntülenme

Erişime Açık

Asymptomatic dermatophyte scalp carriage in school children in Erzincan, Turkey

AYDIN, Merve | GÜLHAN, Barış | GÜMRAL, Ramazan | İLKİT, Macit | ÖZTÜRK, Ali

Background: This study aimed to investigate the prevalence of symptomatic tinea capitis infections of the scalp and its asymptomatic carriage in students attending primary schools in Erzincan, Turkey. Materials and Methods: Eighteen primary schools were visited; 1 located in the central district and 17 located in other districts of the Erzincan province. From 2015 November to 2016 April, scalp scrapings were obtained from a total of 1879 students aged 6 to 13 years (mean age: 9.37±1.69) 924 (49.2%) male and 955 (50.8%) female using sterile hairbrushes, and assessed for tinea capitis and asympt ...Daha fazlası

Konferans Bildirisi 2018 Revista Română de Medicină de Laborator 3 Görüntülenme

Erişime Açık

Subtyping of Blastocystis in Urticarial Patients in Turkey

AYDIN, Merve | YAZICI, Mustafa | DEMİRKAZIK, Mehtap | KOLTAŞ, İsmail Soner | ÇIKMAN, Aytekin | GÜLHAN, Barış | DURAN, Tuğçe | YILMAZ, Aysun | KARA, Murat

Aim: This study aims to investigate Blastocystis’ etiologic role and association with gastrointestinal symptomatology in acute and chronic urticaria patients and to identify Blastocystis subtypes responsible for urticaria. Method: The study included urticaria patients and healthy individuals referred to the Erzincan University Mengücek Gazi Training and Research Hospital Dermatology Polyclinic between June 2015 and May 2017. Participants were divided into Group I (133 patients), subdivided into acute (70) and chronic urticaria patients (63), and Group II (123 control individuals). Blastocystis ...Daha fazlası

Konferans Bildirisi 2018 2 Görüntülenme

Antifungal and anti-biofilm activity of new propane Sulfonyl Hydrazone Against Candida Isolates

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | ÖZDEMİR ÖZMEN, Ummuhan

Candidiasis is the most frequently encountered fungal disease that ranges from mild mucosal infections to serious candidaemia and disseminated candidiasis. There are only limited classes of antifungal agents available for physicians to combat Candida infections. In addition, biofilm cells display phenotypic traits that resulting in enhanced resistance to antifungal drugs. Therefore, the limited option to combat fungal threat has raised the interest in seeking alternative antifungal compounds. The aim of this study was to investigate the antifungal and anti-biofilm activity of the new Sulfonyl ...Daha fazlası

Konferans Bildirisi 2019 5th International Congress on Applied Biological Sciences, Sarajevo-Bosnia&Herzegovina 4 Görüntülenme

Effect of New Sulfonyl Hydrazone Compounds Against Candida Biofilms

AYDIN TERZİOĞLU, Merve | ÖZTÜRK, Ali | DURAN, Tuğçe | ÖZDEMİR ÖZMEN, Ümmühan | ŞUMLU, Esra

Objectives: Candidiasis is the most frequently encountered fungal infection, with ranges from mild superficial infections to disseminated candidiasis. Most manifestations of Candidiasis are associated with biofilm formation. Candida biofilms contributes to therapeutic failure due to resistance to antimicrobial agents and causes an increase in mortality rates. For these reasons, finding new drugs and antimicrobial agents are urgently needed. Sulfonyl hydrazones derived from sulfonamide, are well-known for its pharmacological effects, such as antifungal, antibacterial potential activity. This st ...Daha fazlası

Konferans Bildirisi 2021 The Seventh International Mediterranean Symposium on Medicinal and Aromatic Plants MESMAP – 7 0 Görüntülenme

Expression of Sap Genes 1-10 and Biofilm Formation in Candida Spp. Comparison of Healthcare Associated infectıon isolates from Bloodstream with Isolates from Other Sources

NSANGOU, Ahmed Moustapha | SAMADZADE, Rugiyya | DURAN, Tuğçe | MAÇİN, Salih | AYDIN TERZİOĞLU, Merve | FINDIK, Duygu

Candida species are yeast fungi that are common in nature and can cause both superficial and deep infections. According to recent data, Candida species are considered to be the main causative agents of healthcare-associated infections. In this study, it was aimed to determine Candida species, Sap genes and biofilm formation isolated from blood cultures, which are health care-associated infectious agents, and to evaluate them together with antifungal susceptibility tests. Candida spp. were identified by the Vitek 2 Compact method and then the results were verified by multiplex PCR and DNA seque ...Daha fazlası

Konferans Bildirisi 2022 3 rd International Eurasian Mycology Congress (EMC’22) 6 Görüntülenme

In Vitro Antifungal and Antibiofilm Activity of Artemisinin Against Candida Species

AYDIN TERZİOĞLU, Merve | DURAN, Tuğçe | ŞUMLU, Esra

Artemisinin is a sesquiterpene lactone derivative of Artemisia annua L. Previous research has shown that artemisinin and its derivatives have important pharmacological properties. Candida species are opportunistic infections with high mortality and morbidity rates worldwide. There is growing evidence that natural agents have the ability to treat Candida infections. The demand for new drugs has increased in recent years due to treatment costs, toxicity and resistance to conventional antifungal drugs. The aim of this study was to investigate the antifungal and antibiofilm activity of artemisinin ...Daha fazlası

Konferans Bildirisi 2022 The Eighth International Mediterranean Symposium on Medicinal and Aromatic Plants-MESMAP-8 5 Görüntülenme

Hastanede Yatan COVID-19'lu Hastalar Arasında Akılcı Antibiyotik Kullanımı Mümkün mü?

KARAKOÇ, Hanife Nur | ÖZCAN, Safiye Nur | DİNDAR, Emine Kübra | AYDIN TERZİOĞLU, Merve

GİRİŞ: Antimikrobiyal direnç gelişimi endişe oluştursa da, SARS-CoV-2’nin etken olduğu Koronavirüs Hastalığı 2019 (COVID-19) tedavisinde ampirik antibakteriyeller sıklıkla kullanılmaktadır. COVID-19'lu hastalarda bakteriyel koenfeksiyon insidansı hakkında net bir veri yoktur ve ampirik antibiyotik kullanımına ilişkin sınırlı sayıda klinik çalışma yapılmıştır. Bu çalışmada, SARS-CoV-2 enfeksiyonu nedeniyle hastaneye yatan hastalarda antibiyotik kullanımının incelenmesi amaçlanmıştır. MATERYAL METOD: Bu tek merkezli retrospektif kohort çalışmasına 1 Haziran 2020 ile 1 Haziran 2021 tarihleri aras ...Daha fazlası

Konferans Bildirisi 2021 36. ANKEM Antibiyotik ve Kemoterapi Kongresi Kitabı 6 Görüntülenme

Factors Affecting Adherence to Anti-Retroviral Treatment among HIV/AIDS Patients in Turkey

KARAKOÇ, Hanife Nur | KAYA, Selçuk | AYDIN TERZİOĞLU, Merve | KÖKSAL, İftihar

Objective: Adherence of antiretroviral therapy is critical to succeed in the treatment of HIV infection. There is no approved opinion for the definition of adherence. Patient declaration is one of the commonly used methods to determine treatment compliance. In this study, we aimed to investigate the compliance rate of our patients with high-efficacy antiretroviral therapy, identify factors related to compliance to improve treatment compliance and determine what can be done to increase compliance. Method: 72 patients who admitted to the outpatient clinic with the diagnosis of HIV/AIDS and recei ...Daha fazlası

Konferans Bildirisi 2021 HIV/AIDS Kongresi 0 Görüntülenme

COVID-19 Pnömonisi Olan Hastalarda Yüksek Doz Pulse Kortikosteroid Tedavisinin Prognostik Faktörler Üzerine Etkisi

KARAKOÇ, Hanife Nur | AKSOY, Aysun | AYDIN TERZİOĞLU, Merve | ÖZCAN, Safiye Nur | ZENGİN, Gülçin | AKŞİT YAŞAR, Hacer

Giriş: Çalışmamızda ağır COVID-19 pnömonisi nedeniyle yatarak tedavi alan hastalarda yüksek doz pulse kortikosteroid tedavisinin (YDPKT) etkinliğinin değerlendirilmesi ve 28 günlük mortalite ile ilişkili olası faktörleri belirlenmesi amaçlandı. Gereç ve Yöntem: Bu tek merkezli retrospektif kohort çalışmasına 1 Aralık 2020 ile 1 Haziran 2021 tarihleri arasında Bitlis Tatvan Devlet Hastanesi’nde COVID-19 tanısı ile yatarak tedavi alan hastalar dahil edildi. PCR ile SARS CoV-2 tespit edilen (n=120, %95,2) veya yüksek klinik şüphe ile bilateral pulmoner infiltrat veya lenfopeniye sahip olan klinik ...Daha fazlası

Konferans Bildirisi 2022 10. TÜRKİYE EKMUD BİLİMSEL KONGRESİ 0 Görüntülenme

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Filtreler

Koleksiyon [2]

İlgili Araştırmacılar [14]

Ambargo Durumu [1]

Tam Metin [1]

Yayın Türü [1]

Yazar/lar [20]

Atıf Dizini [3]

Konu Başlıkları [20]

Yayıncı [9]

Yayın Tarihi [4]

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dc.description.provenance [6]